Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.93 |
| ▸ | TP53 | P04637 | 1/20 | 0.93 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.93 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.93 |
| ▸ | TSHR | P16473 | 1/20 | 0.93 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.93 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.93 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.93 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.93 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.87 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.80 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5084980 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5085227 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5087210 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL2733876 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5088202 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL1347880 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL3028771 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL8586767 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL1507558 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL3916850 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596911-B2 | Providing a mixture comprising water and a hydrocarbon; and contacting with onium compound and amine salt for inhibiting the formation of the hydrocarbon hydrates | BAKER HUGHES INCORPORATION | 2003-07-22 | — | — | US | claimed |
| US-20250122418-A1 | Synergistic Blends Of Anti-Agglomerant Gas Hydrate Inhibitors With Quaternary Alkyl Ammonium Compounds | CLARIANT INT LTD (CH) | 2025-04-17 | — | — | US | disclosed |
| US-12129427-B2 | Synergistic blends of anti-agglomerant gas hydrate inhibitors with quaternary alkyl ammonium compounds | CLARIANT INTERNATIONAL LTD (CH) | 2024-10-29 | — | — | US | disclosed |
| US-11898091-B2 | Synergistic blends of anti-agglomerant gas hydrate inhibitors with quaternary benzyl ammonium compounds | CLARIANT INTERNATIONAL LTD (CH) | 2024-02-13 | — | — | US | disclosed |
| EP-4073199-A1 | SYNERGISTIC BLENDS OF ANTI-AGGLOMERANT GAS HYDRATE INHIBITORS WITH QUATERNARY BENZYL AMMONIUM COMPOUNDS | Clariant International Ltd (CH) | 2022-10-19 | — | — | EP | disclosed |
| EP-4073195-A1 | SYNERGISTIC BLENDS OF ANTI-AGGLOMERANT GAS HYDRATE INHIBITORS WITH QUATERNARY ALKYL AMMONIUM COMPOUNDS | Clariant International Ltd (CH) | 2022-10-19 | — | — | EP | disclosed |
| US-20210179918-A1 | Synergistic Blends Of Anti-Agglomerant Gas Hydrate Inhibitors With Quaternary Benzyl Ammonium Compounds | CLARIANT INTERNATIONAL, LTD. (CH) | 2021-06-17 | — | — | US | disclosed |
| WO-2021115967-A1 | SYNERGISTIC BLENDS OF ANTI-AGGLOMERANT GAS HYDRATE INHIBITORS WITH QUATERNARY ALKYL AMMONIUM COMPOUNDS | CLARIANT INTERNATIONAL LTD (CH) | 2021-06-17 | — | — | WO | disclosed |
| WO-2021115969-A1 | SYNERGISTIC BLENDS OF ANTI-AGGLOMERANT GAS HYDRATE INHIBITORS WITH QUATERNARY BENZYL AMMONIUM COMPOUNDS | CLARIANT INTERNATIONAL LTD (CH) | 2021-06-17 | — | — | WO | disclosed |
| WO-2021115973-A1 | SYNERGISTIC BLENDS OF ANTI-AGGLOMERANT GAS HYDRATE INHIBITORS WITH N-ALKANOYL-POLYHYDROXYALKYLAMINES | CLARIANT INTERNATIONAL LTD (CH) | 2021-06-17 | — | — | WO | disclosed |
| US-6372154-B1 | Luminescent ink for printing of organic luminescent devices | CANON KABUSHIKI KAISHA (JP) | 2002-04-16 | — | — | US | disclosed |
| EP-0736130-B1 | A METHOD FOR INHIBITING THE PLUGGING OF CONDUITS BY GAS HYDRATES | SHELL INT RESEARCH (NL) | 1998-07-15 | — | — | EP | disclosed |
| US-5648575-A | Method for inhibiting the plugging of conduits by gas hydrates | SHELL OIL COMPANY (US) | 1997-07-15 | — | — | US | disclosed |
| EP-0736130-A1 | A METHOD FOR INHIBITING THE PLUGGING OF CONDUITS BY GAS HYDRATES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1996-10-09 | — | — | EP | disclosed |
| US-5460728-A | Using quaternary ammonium compound as inhibitor of hydrate formation | SHELL OIL COMPANY (US) | 1995-10-24 | — | — | US | disclosed |
| WO-1995017579-A1 | A METHOD FOR INHIBITING THE PLUGGING OF CONDUITS BY GAS HYDRATES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1995-06-29 | — | — | WO | disclosed |
| EP-0340703-B1 | PROCESS FOR THE PRODUCTION OF FORMYL CYCLOPROPANE | BASF Aktiengesellschaft (DE) | 1992-03-25 | — | — | EP | disclosed |
| US-5053550-A | PREPARATION OF FORMYLCYCLOPROPANE | BASF AKTIENGESELLSCHAFT (DE) | 1991-10-01 | — | — | US | disclosed |
| EP-0340703-A1 | Process for the production of formyl cyclopropane | BASF Aktiengesellschaft (DE) | 1989-11-08 | — | — | EP | disclosed |
| EP-0099259-A1 | Process for producing surface-treated ferromagnetic particles | KONICA CORPORATION (JP) | 1984-01-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12129427-B2 | Synergistic blends of anti-agglomerant gas hydrate inhibitors with quaternary alkyl ammonium compounds | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, RCC1, MTDH | ALDH1A1 3129/4885TP53 1612/4885CYP3A4 3466/4885 |
| US-11898091-B2 | Synergistic blends of anti-agglomerant gas hydrate inhibitors with quaternary benzyl ammonium compounds | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, RCC1, AQP1 | ALDH1A1 3641/4885TP53 2433/4885CYP3A4 3391/4885 |
| US-20250122418-A1 | Synergistic Blends Of Anti-Agglomerant Gas Hydrate Inhibitors With Quaternary Alkyl Ammonium Compounds | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HDHD5, AQP1 | ALDH1A1 3650/4885TP53 647/4885CYP3A4 3663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.