Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.93 |
| ▸ | TP53 | P04637 | 1/20 | 0.93 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.93 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.93 |
| ▸ | TSHR | P16473 | 1/20 | 0.93 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.93 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.93 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.93 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.93 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.87 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.80 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5084980 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5085227 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5087210 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL2733876 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5088202 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL1347880 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL3028771 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL8586767 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5085187 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL1507558 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015180585-A9 | METHOD OF PRODUCING THIAMETHOXAM | ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (CN) | 2016-12-15 | — | — | WO | claimed |
| CN-106029658-A | Method for preparing thiamethoxam | 龙灯农业化工国际有限公司 | 2016-10-12 | — | — | CN | claimed |
| WO-2015180585-A1 | METHOD OF PRODUCING THIAMETHOXAM | ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (CN) | 2015-12-03 | — | — | WO | claimed |
| US-7157006-B2 | Method for perchlorate removal from ground water | THE PENN STATE RESEARCH FOUNDATION (US) | 2007-01-02 | — | — | US | claimed |
| US-20050167366-A1 | Method for perchlorate removal from ground water | THE PENN STATE RESEARCH FOUNDATION | 2005-08-04 | — | — | US | claimed |
| US-6881348-B2 | Method for perchlorate removal from ground water | THE PENN STATE RESEARCH FOUNDATION (US) | 2005-04-19 | — | — | US | claimed |
| US-20030080065-A1 | Method for perchlorate removal from ground water | THE PENN STATE RESEARCH FOUNDATION | 2003-05-01 | — | — | US | claimed |
| WO-2002100509-A1 | A METHOD FOR PERCHLORATE REMOVAL FROM GROUND WATER | THE PENN STATE RESEARCH FOUNDATION (US) | 2002-12-19 | — | — | WO | claimed |
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| EP-0615857-B1 | Recording sheets containing monoammonium compounds | XEROX CORP (US) | 1998-11-11 | — | — | EP | claimed |
| EP-0743574-A2 | Migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| EP-0615857-A1 | Recording sheets containing monoammonium compounds | XEROX CORPORATION (US) | 1994-09-21 | — | — | EP | claimed |
| US-5320902-A | Suitable for use in ink jet printing | XEROX CORPORATION (US) | 1994-06-14 | — | — | US | claimed |
| EP-0075524-B1 | CARBONYLATION PROCESS OF CONJUGATED DIENES IN THE PRESENCE OF A PALLADIUM CATALYST WITH RECYCLING OF SAID CATALYST | RHONE-POULENC CHIMIE DE BASE (FR) | 1984-09-12 | — | — | EP | claimed |
| US-4454333-A | DISTILLATION WITH QUATERNARY PHOSPHONIUM, ARSONIUM OR AMMONIUM | RHONE-POULENC CHIMIE DE BASE (FR) | 1984-06-12 | — | — | US | claimed |
| CN-107840347-B | Titanium-silicon molecular sieve and preparation method and application thereof | 中国石油化工股份有限公司 | 2020-08-18 | — | — | CN | disclosed |
| CN-107840344-B | Titanium-silicon molecular sieve and preparation method and application thereof | 中国石油化工股份有限公司 | 2020-08-18 | — | — | CN | disclosed |
| CN-106029658-B | Method for preparing thiamethoxam | 龙灯农业化工国际有限公司 | 2019-08-16 | — | — | CN | disclosed |
| CN-107840345-B | A kind of application of the preparation method of silica zeolite, processing method and silica zeolite, catalyst and catalyst | 中国石油化工股份有限公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-107840346-B | A kind of application of the preparation method of silica zeolite, processing method and silica zeolite, catalyst and catalyst | 中国石油化工股份有限公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-107840348-A | The preparation method and mesopore molecular sieve and catalyst of a kind of mesopore molecular sieve | 中国石油化工股份有限公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-107840344-A | A kind of HTS and its preparation method and application | 中国石油化工股份有限公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-107840346-A | A kind of application of the preparation method of silica zeolite, processing method and silica zeolite, catalyst and catalyst | 中国石油化工股份有限公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-107840347-A | A kind of HTS and its preparation method and application | 中国石油化工股份有限公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-107840345-A | A kind of application of the preparation method of silica zeolite, processing method and silica zeolite, catalyst and catalyst | 中国石油化工股份有限公司 | 2018-03-27 | — | — | CN | disclosed |
| WO-2015180585-A9 | METHOD OF PRODUCING THIAMETHOXAM | ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (CN) | 2016-12-15 | — | — | WO | disclosed |
| CN-106029658-A | Method for preparing thiamethoxam | 龙灯农业化工国际有限公司 | 2016-10-12 | — | — | CN | disclosed |
| WO-2015180585-A1 | METHOD OF PRODUCING THIAMETHOXAM | ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (CN) | 2015-12-03 | — | — | WO | disclosed |
| US-7572380-B2 | Method for oxyanion removal from ground water | THE PENN STATE RESEARCH FOUNDATION (US) | 2009-08-11 | — | — | US | disclosed |
| US-20090057228-A1 | SYSTEM AND METHOD OF FILTERING USING STRATIFIED ACTIVATED CARBON | SIEMENS WATER TECHNOLOGIES CORP. (US) | 2009-03-05 | — | — | US | disclosed |
| US-20080214386-A1 | Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-04 | — | — | US | disclosed |
| EP-1187833-B1 | METHOD OF PRODUCING THIAMETHOXAM | SYNGENTA PARTICIPATIONS AG (CH) | 2007-06-06 | — | — | EP | disclosed |
| US-7157006-B2 | Method for perchlorate removal from ground water | THE PENN STATE RESEARCH FOUNDATION (US) | 2007-01-02 | — | — | US | disclosed |
| US-20060102562-A1 | Method for oxyanion removal from ground water | THE PENN STATE RESEARCH FOUNDATION | 2006-05-18 | — | — | US | disclosed |
| WO-2006047613-A2 | A METHOD FOR OXYANION REMOVAL FROM GROUND WATER | THE PENN STATE RESEARCH FOUNDATION (US) | 2006-05-04 | — | — | WO | disclosed |
| US-20050167366-A1 | Method for perchlorate removal from ground water | THE PENN STATE RESEARCH FOUNDATION | 2005-08-04 | — | — | US | disclosed |
| US-6881348-B2 | Method for perchlorate removal from ground water | THE PENN STATE RESEARCH FOUNDATION (US) | 2005-04-19 | — | — | US | disclosed |
| US-6747146-B2 | USING PHASE TRANSFER CATALYST AND QUATERNARY AMMONIUM COMPOUND | SYNGENTA CROP PROTECTION, INC. | 2004-06-08 | — | — | US | disclosed |
| US-20030092915-A1 | Method of producing nitroguanidine- and nitroenamine derivatives | SYNGENTA CROP PROTECTION, INC. | 2003-05-15 | — | — | US | disclosed |
| US-20030080065-A1 | Method for perchlorate removal from ground water | THE PENN STATE RESEARCH FOUNDATION | 2003-05-01 | — | — | US | disclosed |
| WO-2002100509-A1 | A METHOD FOR PERCHLORATE REMOVAL FROM GROUND WATER | THE PENN STATE RESEARCH FOUNDATION (US) | 2002-12-19 | — | — | WO | disclosed |
| EP-1187833-A1 | METHOD OF PRODUCING NITROGUANIDINE- AND NITROENAMINE DERIVATIVES | Syngenta Participations AG (CH) | 2002-03-20 | — | — | EP | disclosed |
| WO-2001000623-A1 | METHOD OF PRODUCING NITROGUANIDINE- AND NITROENAMINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-01-04 | — | — | WO | disclosed |
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | disclosed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | disclosed |
| EP-0615857-B1 | Recording sheets containing monoammonium compounds | XEROX CORP (US) | 1998-11-11 | — | — | EP | disclosed |
| EP-0736130-B1 | A METHOD FOR INHIBITING THE PLUGGING OF CONDUITS BY GAS HYDRATES | SHELL INT RESEARCH (NL) | 1998-07-15 | — | — | EP | disclosed |
| US-5714270-A | Multifunctional recording sheets | XEROX CORPORATION (US) | 1998-02-03 | — | — | US | disclosed |
| US-5709976-A | Coated papers | XEROX CORPORATION (US) | 1998-01-20 | — | — | US | disclosed |
| US-5672424-A | Ink jet transparencies | XEROX CORPORATION (US) | 1997-09-30 | — | — | US | disclosed |
| US-5648575-A | Method for inhibiting the plugging of conduits by gas hydrates | SHELL OIL COMPANY (US) | 1997-07-15 | — | — | US | disclosed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | disclosed |
| EP-0743574-A2 | Migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | disclosed |
| EP-0736130-A1 | A METHOD FOR INHIBITING THE PLUGGING OF CONDUITS BY GAS HYDRATES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1996-10-09 | — | — | EP | disclosed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | disclosed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | disclosed |
| US-5460728-A | Using quaternary ammonium compound as inhibitor of hydrate formation | SHELL OIL COMPANY (US) | 1995-10-24 | — | — | US | disclosed |
| WO-1995017579-A1 | A METHOD FOR INHIBITING THE PLUGGING OF CONDUITS BY GAS HYDRATES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1995-06-29 | — | — | WO | disclosed |
| EP-0615857-A1 | Recording sheets containing monoammonium compounds | XEROX CORPORATION (US) | 1994-09-21 | — | — | EP | disclosed |
| US-5320902-A | Suitable for use in ink jet printing | XEROX CORPORATION (US) | 1994-06-14 | — | — | US | disclosed |
| EP-0340408-B1 | PROCESS FOR THE PREPARATION OF 2-HYDROXY-4-(2'-HYDROXYETHOXY)-BENZOPHENONES | BASF Aktiengesellschaft (DE) | 1992-12-09 | — | — | EP | disclosed |
| US-4885396-A | REACTING 2,4-DIHYDROXYBENZOPHENONE WITH ETHYLENE CARBONATE IN PRESENCE OF QUATERNARY AMMONIUM CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 1989-12-05 | — | — | US | disclosed |
| EP-0340408-A1 | Process for the preparation of 2-hydroxy-4-(2'-hydroxyethoxy)-benzophenones | BASF Aktiengesellschaft (DE) | 1989-11-08 | — | — | EP | disclosed |
| EP-0159294-B1 | PROCESS FOR PREPARING CYCLIC PHOSPHOROUS-ACID ESTERS | CIBA-GEIGY AG (CH) | 1988-11-17 | — | — | EP | disclosed |
| US-4692540-A | Process for the preparation of cyclic phosphites | CIBA-GEIGY CORPORATION (US) | 1987-09-08 | — | — | US | disclosed |
| EP-0093363-B1 | PROCESS FOR THE PREPARATION OF DISULPHIDES | CASSELLA Aktiengesellschaft (DE) | 1987-01-14 | — | — | EP | disclosed |
| EP-0159294-A2 | Process for preparing cyclic phosphorous-acid esters | CIBA-GEIGY AG (CH) | 1985-10-23 | — | — | EP | disclosed |
| EP-0093362-B1 | PROCESS FOR THE PREPARATION OF SULFUR DYES OF THE PHTHALOCYANINE SERIES | CASSELLA Aktiengesellschaft (DE) | 1985-02-20 | — | — | EP | disclosed |
| US-4486350-A | REDUCTION OF SULFOCHLORIDE WITH REDUCING AGENT IN PRESENCE OF HYDRIODIC ACID | CASSELLA AKTIENGESELLSCHAFT (DE) | 1984-12-04 | — | — | US | disclosed |
| US-4454333-A | DISTILLATION WITH QUATERNARY PHOSPHONIUM, ARSONIUM OR AMMONIUM | RHONE-POULENC CHIMIE DE BASE (FR) | 1984-06-12 | — | — | US | disclosed |
| EP-0093363-A1 | Process for the preparation of disulphides | CASSELLA Aktiengesellschaft (DE) | 1983-11-09 | — | — | EP | disclosed |
| EP-0093363-A1 | Process for the preparation of disulphides | CASSELLA Aktiengesellschaft (DE) | 1983-11-09 | — | — | EP | disclosed |
| EP-0093362-A1 | Process for the preparation of sulfur dyes of the phthalocyanine series | CASSELLA Aktiengesellschaft (DE) | 1983-11-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092915-A1 | Method of producing nitroguanidine- and nitroenamine derivatives | CBR1, CBR3, NOX1 | ALDH1A1 1306/4885TP53 4701/4885CYP3A4 301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.