Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.93 |
| ▸ | TP53 | P04637 | 1/20 | 0.93 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.93 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.93 |
| ▸ | TSHR | P16473 | 1/20 | 0.93 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.93 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.93 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.93 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.93 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.87 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.80 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5084980 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5085227 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5087210 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL2733876 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5088202 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL1347880 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL3028771 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5085187 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL1507558 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL3916850 | 1.00 | ALDH1A1 (0.93) | ALDH1A1TP53CYP3A4ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043636-B2 | Method for producing triarylorganoborates | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2024-07-23 | — | — | US | disclosed |
| US-20240002409-A1 | METHOD FOR PRODUCING TRIARYLORGANOBORATES | COVESTRO DEUTSCHLAND AG (DE) | 2024-01-04 | — | — | US | disclosed |
| US-11760765-B2 | Method for producing triarylorganoborates | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2023-09-19 | — | — | US | disclosed |
| US-11078218-B2 | Process for the production of triaryl organoborates | COVESTRO DEUTSCHLAND AG (DE) | 2021-08-03 | — | — | US | disclosed |
| US-20190276479-A1 | PROCESS FOR THE PRODUCTION OF TRIARYL ORGANOBORATES | COVESTRO DEUTSCHLAND AG (DE) | 2019-09-12 | — | — | US | disclosed |
| US-5804525-A | BINARY CATALYST OF TERTIARY ORGANIC AMINE AND PHASE TRANSFER CATALYST | GENERAL ELECTRIC COMPANY (US) | 1998-09-08 | — | — | US | disclosed |
| US-5739257-A | INTERFACIAL POLYMERIZATION OF A DIHYDROXY COMPOUND AND PHOSGENE IN THE PRESENCE OF METHYLTRIBUTYLAMMONIUM HALIDE OR HEXABUTYLBUTYLENEDIAMMONIUM HALIDE | GENERAL ELECTRIC COMPANY (US) | 1998-04-14 | — | — | US | disclosed |
| US-5519105-A | CONDENSATION POLYMERIZATION IN THE PRESENCE OF PHASE TRANSFER CATALYST | GENERAL ELECTRIC COMPANY (US) | 1996-05-21 | — | — | US | disclosed |
| EP-0682055-A2 | Binary catalyst for making aromatic polycarbonates | GENERAL ELECTRIC COMPANY (US) | 1995-11-15 | — | — | EP | disclosed |
| US-4933469-A | Method for preparing oxybisphthalimides | GENERAL ELECTRIC COMPANY (US) | 1990-06-12 | — | — | US | disclosed |
| US-4585638-A | Synthesis of crystalline silicate ZSM-5 | MOBIL OIL CORPORATION (US) | 1986-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240002409-A1 | METHOD FOR PRODUCING TRIARYLORGANOBORATES | KMO, COASY, CYP3A4 | ALDH1A1 2226/4885TP53 3652/4885CYP3A4 3/4885 |
| US-11078218-B2 | Process for the production of triaryl organoborates | OR10J3, CYP4F3, CYP4B1 | ALDH1A1 3058/4885TP53 4158/4885CYP3A4 11/4885 |
| US-12043636-B2 | Method for producing triarylorganoborates | KMO, COASY, CYP3A4 | ALDH1A1 2226/4885TP53 3652/4885CYP3A4 3/4885 |
| US-11760765-B2 | Method for producing triarylorganoborates | CYP3A4, CYP3A43, CYP4B1 | ALDH1A1 1623/4885TP53 3682/4885CYP3A4 1/4885 |
| US-20190276479-A1 | PROCESS FOR THE PRODUCTION OF TRIARYL ORGANOBORATES | CYP1B1, CYP3A4, CYP4B1 | ALDH1A1 1943/4885TP53 3930/4885CYP3A4 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.