Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | IL1RN | P18510 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 2/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | NMBR | P28336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1855025 | 0.99 | NOS1 (0.38) | NOS1SMN1; SMN2ITGB3ITGA2BCTSL | |
| SCHEMBL5157777 | 0.95 | NOS1 (0.41) | NOS1SMN1; SMN2ITGB3ITGA2BCTSL | |
| Hydrochloric Acid SCHEMBL3180458 | 0.95 | ITGB3 (0.38) | NOS1SMN1; SMN2ITGB3ITGA2BCTSL | |
| Hydrochloric Acid SCHEMBL1021511 | 0.94 | NOS1 (0.40) | NOS1SMN1; SMN2ITGB3ITGA2BCTSL | |
| Hydrochloric Acid SCHEMBL5571043 | 0.94 | NOS1 (0.40) | NOS1SMN1; SMN2ITGB3ITGA2BCTSL | |
| SCHEMBL13479152 | 0.93 | NOS1 (0.36) | NOS1SMN1; SMN2ITGB3ITGA2BCTSL | |
| SCHEMBL13479149 | 0.92 | NOS1 (0.40) | NOS1SMN1; SMN2ITGB3ITGA2BCTSL | |
| SCHEMBL13479144 | 0.91 | ITGB3 (0.41) | NOS1SMN1; SMN2ITGB3ITGA2BCTSL | |
| SCHEMBL13479142 | 0.91 | NOS1 (0.38) | NOS1SMN1; SMN2ITGB3ITGA2BCTSL | |
| SCHEMBL13479135 | 0.90 | TACR1 (0.43) | CTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655643-B2 | Antibacterial macrocycles with substituted biphenyl | AICURIS GMBH & CO. KG (DE) | 2010-02-02 | — | — | US | disclosed |
| US-20070099885-A1 | Antibacterial macrocycles with substituted biphenyl | AICURIS GMBH & CO. KG (DE) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099885-A1 | Antibacterial macrocycles with substituted biphenyl | NOD2, AHR, BCL2 | NOS1 4698/4885SMN1; SMN2 3554/4885ITGB3 4113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.