Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.40 |
| ▸ | TYR | P14679 | 2/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | IL1RN | P18510 | 1/20 | 0.39 |
| ▸ | NMBR | P28336 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5571043 | 0.99 | NOS1 (0.40) | NOS1SMN1; SMN2CTSKCTSLCTSS | |
| Hydrochloric Acid SCHEMBL1021511 | 0.99 | NOS1 (0.40) | NOS1SMN1; SMN2CTSKCTSLCTSS | |
| SCHEMBL13479149 | 0.96 | NOS1 (0.40) | NOS1SMN1; SMN2CTSKCTSLCTSS | |
| SCHEMBL13479144 | 0.96 | ITGB3 (0.41) | NOS1SMN1; SMN2CTSKCTSLCTSS | |
| SCHEMBL13479142 | 0.95 | NOS1 (0.38) | NOS1SMN1; SMN2CTSKCTSLCTSS | |
| SCHEMBL13479140 | 0.95 | NOS1 (0.38) | NOS1SMN1; SMN2CTSKCTSLCTSS | |
| Hydrochloric Acid SCHEMBL1855025 | 0.94 | NOS1 (0.38) | NOS1SMN1; SMN2CTSKCTSLCTSS | |
| SCHEMBL14497717 | 0.94 | CTSL (0.44) | NOS1SMN1; SMN2CTSKCTSLCTSS | |
| SCHEMBL13479152 | 0.93 | NOS1 (0.36) | NOS1SMN1; SMN2CTSKCTSLCTSS | |
| SCHEMBL13479143 | 0.93 | GSTP1 (0.40) | NOS1SMN1; SMN2CTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515983-B1 | ANTIBACTERIAL AMIDE MACROCYCLES | AICURIS GMBH & CO KG (DE) | 2007-02-21 | — | — | EP | disclosed |
| EP-1526896-A1 | ANTIBACTERIAL ESTER MACROCYCLES | Bayer HealthCare AG (DE) | 2005-05-04 | — | — | EP | disclosed |
| WO-2004012816-A1 | ANTIBACTERIAL ESTER MACROCYCLES | BAYER HEALTHCARE AG (DE) | 2004-02-12 | — | — | WO | disclosed |