Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CTSL | P07711 | 6/20 | 0.38 |
| ▸ | CTSB | P07858 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13479143 | 0.96 | GSTP1 (0.40) | GSTP1GSTM2ALDH1A1CTSLCTSB | |
| SCHEMBL13479134 | 0.90 | GSTP1 (0.44) | GSTP1GSTM2ALDH1A1CTSLCTSB | |
| SCHEMBL5157777 | 0.89 | NOS1 (0.41) | CTSLCTSBMAPTSMN1; SMN2ITGB3 | |
| SCHEMBL13479131 | 0.89 | BCL2 (0.43) | GSTP1GSTM2CTSLCTSBMAPT | |
| Hydrochloric Acid SCHEMBL5571043 | 0.88 | NOS1 (0.40) | CTSLCTSBMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL1021511 | 0.88 | NOS1 (0.40) | CTSLCTSBMEN1KMT2AMAPT | |
| SCHEMBL13479174 | 0.85 | GSTP1 (0.40) | GSTP1GSTM2ALDH1A1CTSLCTSB | |
| SCHEMBL13479149 | 0.85 | NOS1 (0.40) | CTSLCTSBMAPTPOLBSMN1; SMN2 | |
| SCHEMBL13479144 | 0.85 | ITGB3 (0.41) | ALDH1A1CTSLCTSBMAPTPOLB | |
| SCHEMBL14497720 | 0.84 | SMN1; SMN2 (0.39) | CTSLCTSBSMN1; SMN2CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655643-B2 | Antibacterial macrocycles with substituted biphenyl | AICURIS GMBH & CO. KG (DE) | 2010-02-02 | — | — | US | disclosed |
| US-20070099885-A1 | Antibacterial macrocycles with substituted biphenyl | AICURIS GMBH & CO. KG (DE) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099885-A1 | Antibacterial macrocycles with substituted biphenyl | NOD2, AHR, BCL2 | GSTP1 1034/4885GSTM2 2685/4885ALDH1A1 2817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.