SCHEMBL134822

SCHEMBL134822

CC(Br)(c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.52
ALDH1A1 P00352 3/20 0.48
TAAR1 Q96RJ0 1/20 0.48
ALOX15 P16050 1/20 0.48
ESR1 P03372 2/20 0.46
ESR2 Q92731 2/20 0.46
CYP3A4 P08684 1/20 0.46
KCNN4 O15554 4/20 0.46
TSHR P16473 2/20 0.45
MAPT P10636 1/20 0.44
KMT2A Q03164 1/20 0.44
CYP2C19 P33261 1/20 0.42
HIF1A Q16665 1/20 0.42
CYP2B6 P20813 1/20 0.41
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8317449 0.84 ALDH1A1 (0.67) MAPK1ALDH1A1TAAR1ESR1ESR2
SCHEMBL642315 0.83 TAAR1 (0.57) MAPK1ALDH1A1TAAR1ALOX15ESR1
Hydrogen Peroxide SCHEMBL9448960 0.80 ALDH1A1 (0.55) MAPK1ALDH1A1TAAR1ALOX15ESR1
SCHEMBL686328 0.80 MAPK1 (0.52) MAPK1ALDH1A1TAAR1ALOX15ESR1
SCHEMBL6280946 0.80 MAPK1 (0.52) MAPK1ALDH1A1TAAR1ALOX15ESR1
Tert-Butylbenzene SCHEMBL27459137 0.78 MAPK1 (0.50) MAPK1ALDH1A1TAAR1ALOX15ESR1
SCHEMBL96177 0.76 MAPK1 (0.55) MAPK1ALDH1A1TAAR1ALOX15ESR1
Tert-Butylbenzene SCHEMBL22264597 0.76 MAPK1 (0.55) MAPK1ALDH1A1TAAR1ALOX15ESR1
Tert-Butylbenzene SCHEMBL22264599 0.76 MAPK1 (0.55) MAPK1ALDH1A1TAAR1ALOX15ESR1
Tert-Butylbenzene SCHEMBL18889 0.76 MAPK1 (0.55) MAPK1ALDH1A1TAAR1ALOX15ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118480244-A ABS composite material and preparation method and application thereof 上海金发科技发展有限公司 2024-08-13 CN claimed
CN-117286714-A Manufacturing method of cellulose fiber flame-retardant non-woven fabric 合肥洁尔卫生新材料有限公司 2023-12-26 CN claimed
CN-116836504-A Flame-retardant plastic and preparation method thereof 镇江宇烨新材料科技有限公司 2023-10-03 CN claimed
US-20210009778-A1 FLAME-RESISTANT FOAMED STYRENE-BASED RESIN COMPOSITION DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2021-01-14 US claimed
EP-3670585-A1 FLAME-RESISTANT FOAMED STYRENE-BASED RESIN COMPOSITION Dai-Ichi Kogyo Seiyaku Co., Ltd. (JP) 2020-06-24 EP claimed
CN-107075202-B Use of organooxyimide salts as flame retardants, flame-retardant plastic compositions, method for the production thereof and moulded parts, paints or coatings 弗劳恩霍弗应用研究促进协会 2020-06-16 CN claimed
CN-111032755-A Flame-retardant expandable styrene resin composition 第一工业制药株式会社 2020-04-17 CN claimed
EP-2839863-B1 Method for deactivating brominated derivatives contained in plastic materials JULELO (FR) 2019-10-02 EP claimed
EP-2426165-B1 FLAME-RETARDANT EXPANDABLE STYRENE RESIN COMPOSITION DAI ICHI KOGYO SEIYAKU CO LTD (JP) 2016-06-29 EP claimed
CN-105440689-A Silicon-antimony composite flame retardant, and preparation method and applications thereof DONGGUAN CALVIN PLASTIC & TECH CO LTD 2016-03-30 CN claimed
US-20090012217-A1 Flameproof Thermoplastic Resin Composition CHEIL INDUSTRIES INC. (KR) 2009-01-08 US claimed
CN-101338070-A Flameproof thermoplastic resin composition CHEIL IND INC (KR) 2009-01-07 CN claimed
US-20080221255-A1 Thermoplastic Resin Composition Having Improved Impact Resistance, Color Development and Good Flame-Retardance CHEIL INDUSTRIES INC. (KR) 2008-09-11 US claimed
CN-101260213-A Thermoplastic resin composition having improved impact resistance, color development and good flame-retardance CHEIL IND INC (KR) 2008-09-10 CN claimed
WO-2008082138-A1 THERMOPLASTIC RESIN COMPOSITION HAVING IMPROVED IMPACT RESISTANCE CHEIL INDUSTRIES INC. (KR) 2008-07-10 WO claimed
US-20080160240-A1 Thermoplastic Resin Composition Having Improved Impact Resistance CHEIL INDUSTRIES INC. (KR) 2008-07-03 US claimed
EP-0673396-B1 PROCESS FOR PRODUCING POLYPROPYLENE MATERIALS GRAFTED WITH AN EPOXYALKYL ACRYLATE COMPOUND BOREALIS AS (DK) 1998-07-08 EP claimed
EP-0673396-A1 PROCESS FOR PRODUCING POLYPROPYLENE MATERIALS GRAFTED WITH AN EPOXYALKYL ACRYLATE COMPOUND Den Norske Stats Oljeselskap A.S. (NO) 1995-09-27 EP claimed
WO-1994013719-A1 POLYPROPYLENE MATERIALS GRAFTED WITH AN EPOXYALKYL ACRYLATE COMPOUND DEN NORSKE STATS OLJESELSKAP A.S. (NO) 1994-06-23 WO claimed
CN-1077758-A Graphite anode for electrolysis of chloride aqueous solution and method for producing same BEIJING INST OF CHEMICAL METAL (CN) 1993-10-27 CN claimed