Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8269667 | 0.83 | ALDH1A1 (0.50) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL642315 | 0.83 | TAAR1 (0.57) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL28223138 | 0.83 | RIPK1 (0.45) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL22032944 | 0.81 | MAPK1 (0.42) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL134822 | 0.80 | MAPK1 (0.52) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| Hydrogen Peroxide SCHEMBL9448960 | 0.80 | ALDH1A1 (0.55) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL686328 | 0.80 | MAPK1 (0.52) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| Tert-Butylbenzene SCHEMBL27650352 | 0.78 | MAPK1 (0.50) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL1514215 | 0.78 | MAPK1 (0.50) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL3687465 | 0.78 | MAPK1 (0.50) | MAPK1ALDH1A1TAAR1ALOX15ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6967229-B2 | Carbon-carbon initiators for use in golf balls | ACUSHNET COMPANY (US) | 2005-11-22 | — | — | US | claimed |
| US-20050009992-A1 | Carbon-carbon initiators for use in golf balls | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2005-01-13 | — | — | US | claimed |
| US-9056227-B2 | Golf ball comprising a core having a shallow hardness gradient | ACUSHNET COMPANY (US) | 2015-06-16 | — | — | US | disclosed |
| US-8968117-B2 | Dual-core comprising zero gradient center and positive gradient outer core layer | ACUSHNET COMPANY (US) | 2015-03-03 | — | — | US | disclosed |
| US-20130109504-A1 | DUAL-CORE COMPRISING ZERO GRADIENT CENTER AND POSITIVE GRADIENT OUTER CORE LAYER | ACUSHNET COMPANY (US) | 2013-05-02 | — | — | US | disclosed |
| US-20130109506-A1 | GOLF BALL COMPRISING A CORE HAVING A SHALLOW HARDNESS GRADIENT | ACUSHNET COMPANY (US) | 2013-05-02 | — | — | US | disclosed |
| US-6967229-B2 | Carbon-carbon initiators for use in golf balls | ACUSHNET COMPANY (US) | 2005-11-22 | — | — | US | disclosed |
| US-20050009992-A1 | Carbon-carbon initiators for use in golf balls | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2005-01-13 | — | — | US | disclosed |
| EP-0144015-B1 | SELF-EXTINGUISHING COMPOSITIONS BASED ON ETHYLENE VINYLACETATE COPOLYMERS SUITABLE FOR THE PREPARATION OF FOAMED MATERIALS | MONTEDIPE S.p.A. (IT) | 1988-09-14 | — | — | EP | disclosed |
| EP-0144015-A1 | Self-extinguishing compositions based on ethylene vinylacetate copolymers suitable for the preparation of foamed materials | MONTEDIPE S.p.A. (IT) | 1985-06-12 | — | — | EP | disclosed |