SCHEMBL17733010

SCHEMBL17733010

Cc1cc(C)c(OC(F)(F)C(F)=C(F)F)c(F)c1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.31
AR P10275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17733025 0.91 NOTUM (0.33) NOTUM
SCHEMBL13484249 0.78 FFAR4 (0.38) AR
SCHEMBL15889082 0.70 CETP (0.35) NOTUM
SCHEMBL15889065 0.70 NOTUM (0.31) NOTUM
SCHEMBL23447294 0.68 NOTUM (0.43) NOTUM
SCHEMBL10052628 0.68 ACHE (0.36)
SCHEMBL17662618 0.68 ACHE (0.46)
SCHEMBL10968659 0.68
SCHEMBL15889077 0.66 CES2 (0.31)
SCHEMBL14424434 0.65 FFAR4 (0.42) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1840185-B1 LIQUID CRYSTAL COMPOSITION ADEKA CORP (JP) 2016-05-11 EP disclosed