SCHEMBL24749508

SCHEMBL24749508

Cc1cc(F)c(OC(F)(F)F)c(C#N)c1

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AR P10275 14/20 0.39
CYP11B1 P15538 2/20 0.33
CYP11B2 P19099 2/20 0.33
TRPV4 Q9HBA0 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10052628 0.81 ACHE (0.36)
SCHEMBL13484249 0.76 FFAR4 (0.38) AR
SCHEMBL29159716 0.72 KIF11 (0.37) ARTRPV4
SCHEMBL405549 0.71 TRPV4 (0.39) ARCYP11B1CYP11B2TRPV4
SCHEMBL14033196 0.71 TRPV4 (0.39) ARCYP11B1CYP11B2TRPV4
SCHEMBL2665024 0.70 AR (0.49) AR
SCHEMBL404723 0.68 ADRB2 (0.45) ARCYP11B1CYP11B2TRPV4
SCHEMBL13855817 0.68 SELL (0.41) ARCYP11B1CYP11B2TRPV4
SCHEMBL25910696 0.68 CYP11B1 (0.37) ARCYP11B1CYP11B2TRPV4
SCHEMBL20095956 0.68 CYP11B1 (0.37) ARCYP11B1CYP11B2TRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4105201-A1 AN ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING A SUBSTRATE, AN ANODE LAYER AND A CATHODE LAYER, AT LEAST ONE LIGHT EMITTING LAYER, AND AT LEAST ONE SEMICONDUCTOR LAYER THAT COMPRISES AT LEAST ONE METAL COMPOUND OF A METAL AND AT LEAST ONE LIGAND Novaled GmbH (DE) 2022-12-21 EP disclosed