Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 8/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PFKFB3 | Q16875 | 7/20 | 0.52 |
| ▸ | PFKFB4 | Q16877 | 6/20 | 0.52 |
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12032437 | 0.93 | LMNA (0.64) | CMA1LMNAHTTPFKFB3PFKFB4 | |
| SCHEMBL27685 | 0.87 | PFKFB4 (0.66) | CMA1LMNAHTTPFKFB3PFKFB4 | |
| SCHEMBL12220857 | 0.78 | LMNA (0.81) | LMNAHTTMETAP2ALDH1A1 | |
| SCHEMBL2913594 | 0.77 | CMA1 (0.66) | CMA1PFKFB3PFKFB4NPSR1L3MBTL1 | |
| SCHEMBL2912928 | 0.77 | CMA1 (0.81) | CMA1PFKFB3PFKFB4NPSR1L3MBTL1 | |
| SCHEMBL13077397 | 0.76 | LMNA (0.53) | LMNAHTTMETAP2ALDH1A1 | |
| SCHEMBL2908164 | 0.75 | CMA1 (0.76) | CMA1PFKFB3PFKFB4NPSR1L3MBTL1 | |
| SCHEMBL13484207 | 0.75 | LMNA (0.72) | LMNAHTTMETAP2ALDH1A1 | |
| SCHEMBL4452960 | 0.74 | PFKFB3 (0.75) | CMA1PFKFB3PFKFB4NPSR1L3MBTL1 | |
| SCHEMBL16715765 | 0.74 | NPSR1 (0.58) | CMA1PFKFB3PFKFB4NPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7659272-B2 | CCR9 inhibitors and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-02-09 | — | — | US | disclosed |