Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13848655 | 0.82 | KDM4E (0.34) | ALOX15KDM4EALDH1A1GAANPC1 | |
| SCHEMBL13484333 | 0.73 | FAAH (0.46) | ALOX15KDM4EALDH1A1NPC1HSD17B10 | |
| SCHEMBL13484020 | 0.71 | ENPP3 (0.44) | ALOX15KDM4EALDH1A1GAANPC1 | |
| SCHEMBL23791344 | 0.68 | CA12 (0.31) | — | |
| SCHEMBL22276368 | 0.66 | — | — | |
| SCHEMBL27719352 | 0.66 | MAOB (0.40) | SLC6A3ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL13848524 | 0.64 | HTR2C (0.32) | — | |
| SCHEMBL439225 | 0.63 | KDM4E (0.49) | ALOX15KDM4EALDH1A1GAANPC1 | |
| SCHEMBL13848629 | 0.63 | ENPP3 (0.44) | LMNA | |
| SCHEMBL12299144 | 0.62 | HDAC1 (0.36) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662971-B2 | enzyme inhibitor for treating sleep disorders | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-02-16 | — | — | US | disclosed |