Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | ALPG | P10696 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447117 | 0.89 | THRB (0.43) | LMNAHTTPOLBAPEX1TDP1 | |
| SCHEMBL20671287 | 0.86 | THRB (0.43) | HTTPOLBAPEX1TDP1THRB | |
| SCHEMBL3138267 | 0.85 | THRB (0.40) | LMNAHTTPOLBAPEX1TDP1 | |
| SCHEMBL8982153 | 0.83 | THRB (0.39) | LMNAHTTPOLBAPEX1TDP1 | |
| SCHEMBL7519970 | 0.82 | CYP2C19 (0.50) | LMNAHTTALPGPOLBAPEX1 | |
| SCHEMBL13261677 | 0.80 | THRB (0.40) | LMNAHTTPOLBAPEX1TDP1 | |
| SCHEMBL13696520 | 0.78 | CYP2C19 (0.43) | LMNAHTTPOLBAPEX1TDP1 | |
| SCHEMBL4457186 | 0.78 | CYP1A2 (0.40) | LMNAHTTPOLBAPEX1TDP1 | |
| SCHEMBL12960322 | 0.77 | HRH3 (0.42) | HTTPOLBAPEX1TDP1THRB | |
| SCHEMBL13261678 | 0.76 | TDP1 (0.36) | LMNAHTTPOLBAPEX1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185633-B1 | METHOD OF PREPARING A NANOPARTICLE DISPERSION OF A MODIFIED METAL OXIDE | CABOT CORP (US) | 2014-03-12 | — | — | EP | disclosed |
| US-7662879-B2 | Compositions comprising modified metal oxides | CABOT CORPORATION (US) | 2010-02-16 | — | — | US | disclosed |
| US-20070208122-A1 | Compositions comprising modified metal oxides | CABOT CORPORATION | 2007-09-06 | — | — | US | disclosed |