Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447117 | 0.95 | THRB (0.43) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL12960322 | 0.91 | HRH3 (0.42) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL8982153 | 0.90 | THRB (0.39) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL7519970 | 0.88 | CYP2C19 (0.50) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL13261677 | 0.86 | THRB (0.40) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL13484338 | 0.85 | LMNA (0.36) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL13696520 | 0.84 | CYP2C19 (0.43) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL4457186 | 0.84 | CYP1A2 (0.40) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL12960353 | 0.82 | MCHR1 (0.36) | POLBTDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL14139774 | 0.82 | TDP1 (0.36) | THRBPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139878-A2 | HIGH REFRACTIVE INDEX MONOMERS, COMPOSITIONS AND USES THEREOF | BASF SE (DE) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008101806-A2 | HIGH REFRACTIVE INDEX MONOMERS, COMPOSITIONS AND USES THEREOF | BASF SE (CH) | 2008-08-28 | — | — | WO | disclosed |
| WO-2008101806-A2 | HIGH REFRACTIVE INDEX MONOMERS, COMPOSITIONS AND USES THEREOF | BASF SE (CH) | 2008-08-28 | — | — | WO | disclosed |
| US-20080200582-A1 | High refractive index monomers, compositions and uses thereof | CIBA CORP. | 2008-08-21 | — | — | US | disclosed |
| US-20080200582-A1 | High refractive index monomers, compositions and uses thereof | CIBA CORP. | 2008-08-21 | — | — | US | disclosed |
| US-20080200582-A1 | High refractive index monomers, compositions and uses thereof | CIBA CORP. | 2008-08-21 | — | — | US | disclosed |