Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447117 | 0.94 | THRB (0.43) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL3138267 | 0.90 | THRB (0.40) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL7519970 | 0.87 | CYP2C19 (0.50) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL13261677 | 0.85 | THRB (0.40) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL4536017 | 0.84 | THRB (0.48) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL13484338 | 0.83 | LMNA (0.36) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL4294879 | 0.82 | THRB (0.47) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL13696520 | 0.82 | CYP2C19 (0.43) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL4457186 | 0.82 | CYP1A2 (0.40) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL12960322 | 0.81 | HRH3 (0.42) | THRBPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090220770-A1 | POLYMERIZABLE COMPOSITION, HIGH-REFRACTIVE-INDEX RESIN COMPOSITION, AND OPTICAL MEMBER MADE OF THE SAME | MITSUBISHI CHEMICAL CORPORATION (JP) | 2009-09-03 | — | — | US | disclosed |
| US-20090220770-A1 | POLYMERIZABLE COMPOSITION, HIGH-REFRACTIVE-INDEX RESIN COMPOSITION, AND OPTICAL MEMBER MADE OF THE SAME | MITSUBISHI CHEMICAL CORPORATION (JP) | 2009-09-03 | — | — | US | disclosed |
| EP-0562861-B1 | Optical materials with a high refractive index and method for producing the same | MITSUBISHI CHEM CORP (JP) | 1996-05-29 | — | — | EP | disclosed |
| US-5424339-A | Addition polymerization of sulfur-containing acrylates and hydroxy acrylates folowed by reaction with diisocyanates | MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0562861-A1 | Optical materials with a high refractive index and method for producing the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 1993-09-29 | — | — | EP | disclosed |