SCHEMBL4447117

SCHEMBL4447117

C=C(C)C(=O)OCCSCc1ccc(CSCCOC(=O)C(=C)C)cc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.43
POLB P06746 1/20 0.42
APEX1 P27695 1/20 0.42
HTT P42858 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
TSHR P16473 3/20 0.42
CYP2C19 P33261 1/20 0.39
ALDH1A1 P00352 6/20 0.38
LMNA P02545 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
PKM P14618 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HPGD P15428 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3138267 0.95 THRB (0.40) THRBPOLBAPEX1HTTTDP1
SCHEMBL8982153 0.94 THRB (0.39) THRBPOLBAPEX1HTTTDP1
SCHEMBL7519970 0.92 CYP2C19 (0.50) THRBPOLBAPEX1HTTTDP1
SCHEMBL13261677 0.90 THRB (0.40) THRBPOLBAPEX1HTTTDP1
SCHEMBL13484338 0.89 LMNA (0.36) THRBPOLBAPEX1HTTTDP1
SCHEMBL13696520 0.88 CYP2C19 (0.43) THRBPOLBAPEX1HTTTDP1
SCHEMBL4457186 0.88 CYP1A2 (0.40) THRBPOLBAPEX1HTTTDP1
SCHEMBL12960322 0.87 HRH3 (0.42) THRBPOLBAPEX1HTTTDP1
SCHEMBL14139774 0.85 TDP1 (0.36) THRBPOLBAPEX1HTTTDP1
SCHEMBL13261678 0.85 TDP1 (0.36) THRBPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0716102-B1 TRANSPARENT PLASTIC MATERIAL, OPTICAL ARTICLE MADE THEREFROM, AND PRODUCTION PROCESS SEIKO EPSON CORP (JP) 2002-02-06 EP claimed
US-7569619-B2 Radiation-curable resin composition and cured product thereof MITSUBISHI CHEMICAL CORPORATION (JP) 2009-08-04 US disclosed
WO-2008101806-A2 HIGH REFRACTIVE INDEX MONOMERS, COMPOSITIONS AND USES THEREOF BASF SE (CH) 2008-08-28 WO disclosed
US-20080200582-A1 High refractive index monomers, compositions and uses thereof CIBA CORP. 2008-08-21 US disclosed
US-20080200582-A1 High refractive index monomers, compositions and uses thereof CIBA CORP. 2008-08-21 US disclosed
US-20080200582-A1 High refractive index monomers, compositions and uses thereof CIBA CORP. 2008-08-21 US disclosed
US-20080102262-A1 Radiation Curable Composition and Curing Product Thereof, and Laminate Including the Same MITSUBISHI CHEMICAL CORPORATION (JP) 2008-05-01 US disclosed
US-20070231527-A1 Optical Recording Medium and Method for Producing Same MITSUBISHI KAGAKU MEDIA CO., LTD. (JP) 2007-10-04 US disclosed
EP-1811517-A1 OPTICAL RECORDING MEDIUM AND METHOD FOR PRODUCING SAME Mitsubishi Kagaku Media Co., Ltd. (JP) 2007-07-25 EP disclosed
US-7006344-B2 Capacitor comprising bis(4-mercaptophenyl) sulfide derivative MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2006-02-28 US disclosed
US-20050267230-A1 Radiation-curable resin composition and cured product thereof MITSUBISHI CHEMICAL CORPORATION (JP) 2005-12-01 US disclosed
EP-1561765-A1 RADIATION CURING RESIN COMPOSITION AND CURED PRODUCT THEREOF Mitsubishi Chemical Corporation (JP) 2005-08-10 EP disclosed
US-20030189808-A1 Bis(4-mercaptophenyl)sulfide derivatives, process for the preparation thereof and electronic components MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2003-10-09 US disclosed
EP-0940694-B1 Photochromic curable composition TOKUYAMA CORP (JP) 2002-08-14 EP disclosed
EP-0716102-B1 TRANSPARENT PLASTIC MATERIAL, OPTICAL ARTICLE MADE THEREFROM, AND PRODUCTION PROCESS SEIKO EPSON CORP (JP) 2002-02-06 EP disclosed
US-6194511-B1 COMPRISING POLYMERIZABLE MONOMER CONTAINING SULFUR-CONTAINING (METH)ACRYLATE POLYMERIZABLE MONOMER AND PHOTOCHROMIC COMPOUND TOKUYAMA CORPORATION (JP) 2001-02-27 US disclosed
EP-0940694-A1 Photochromic curable composition TOKUYAMA CORPORATION (JP) 1999-09-08 EP disclosed
US-5792822-A COMPRISING A METAL COMPLEXES AS ULTRAVIOLET LIGHT ADSORBER AND BLOCKING AGENT; RADIATION RESISTANCE, LIGHTWEIGHT, STABILITY; EYEGLASS LENS, CONTACT LENS, DISPLAY FILTER SEIKO EPSON CORPORATION (JP) 1998-08-11 US disclosed
EP-0716102-A1 TRANSPARENT PLASTIC MATERIAL, OPTICAL ARTICLE MADE THEREFROM, AND PRODUCTION PROCESS SEIKO EPSON CORPORATION (JP) 1996-06-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030189808-A1 Bis(4-mercaptophenyl)sulfide derivatives, process for the preparation thereof and electronic components SULT1E1, CBS, EPB41 THRB 4520/4885POLB 3754/4885APEX1 479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.