Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.55 |
| ▸ | TACR1 | P25103 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.43 |
| ▸ | PAK4 | O96013 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14359179 | 0.89 | HSP90AA1 (0.56) | HSP90AA1TACR1RAB9ANPC1POLB | |
| SCHEMBL5104857 | 0.89 | HSP90AA1 (0.59) | HSP90AA1TACR1RAB9ANPC1POLB | |
| SCHEMBL16510056 | 0.88 | POLB (0.60) | HSP90AA1TACR1RAB9ANPC1POLB | |
| SCHEMBL13485747 | 0.87 | HSP90AA1 (0.54) | HSP90AA1TACR1RAB9ANPC1POLB | |
| SCHEMBL16268556 | 0.79 | HSP90AA1 (0.53) | HSP90AA1TACR1RAB9ANPC1POLB | |
| SCHEMBL24234038 | 0.77 | RIPK1 (0.60) | HSP90AA1POLBRIPK1 | |
| SCHEMBL14646676 | 0.76 | TACR1 (0.59) | HSP90AA1TACR1RAB9ANPC1POLB | |
| SCHEMBL18286135 | 0.75 | HSP90AA1 (0.52) | HSP90AA1TACR1RAB9ANPC1P2RX7 | |
| SCHEMBL21732983 | 0.74 | HSP90AA1 (0.50) | HSP90AA1TACR1RAB9ANPC1POLB | |
| SCHEMBL18711396 | 0.73 | POLB (0.61) | POLBRIPK1MEN1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100036126-A1 | STEREOSELECTIVE SYNTHESIS OF (S)-1-METHYL-3-PHENYLPIPERAZINE | N.V. ORGANON (NL) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036126-A1 | STEREOSELECTIVE SYNTHESIS OF (S)-1-METHYL-3-PHENYLPIPERAZINE | THOP1, PRSS1, DPEP1 | HSP90AA1 1408/4885TACR1 2777/4885RAB9A 4674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.