Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13482 | 0.88 | LSS (0.35) | DRD3SLC6A9KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11994167 | 0.77 | BRD4 (0.43) | SLC6A9KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8976521 | 0.73 | BRD4 (0.48) | SLC6A9KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL14792983 | 0.71 | ALDH1A1 (0.46) | SLC6A9KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL13435 | 0.71 | BRD4 (0.43) | SLC6A9KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13828379 | 0.71 | L3MBTL1 (0.48) | MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL13828388 | 0.70 | BRD4 (0.42) | SLC6A9MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL8375772 | 0.68 | GCGR (0.45) | — | |
| SCHEMBL10012 | 0.68 | CYP2C9 (0.40) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14792982 | 0.68 | BRD4 (0.40) | SLC6A9KDM4EMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041462-A2 | POLYCYCLIC COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS, INC. (US) | 2011-04-07 | — | — | WO | disclosed |