Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13486214 | 0.85 | PRSS1 (0.41) | PRSS1TMPRSS15CARM1PRMT6ALOX15 | |
| SCHEMBL3204847 | 0.85 | EPHX2 (0.38) | PRSS1TMPRSS15CARM1PRMT6 | |
| SCHEMBL3209730 | 0.81 | LMNA (0.49) | TAS1R3TAS1R1 | |
| SCHEMBL3201265 | 0.78 | — | — | |
| SCHEMBL3204839 | 0.76 | PRSS1 (0.36) | PRSS1TMPRSS15CARM1PRMT6ALOX15 | |
| SCHEMBL3212402 | 0.76 | BRD4 (0.48) | — | |
| Hydrochloric Acid SCHEMBL3191227 | 0.76 | PTGDR (0.39) | PRSS1TMPRSS15 | |
| Hydrochloric Acid SCHEMBL3191222 | 0.73 | PTGDR (0.37) | PRSS1TMPRSS15CARM1PRMT6 | |
| SCHEMBL27936118 | 0.71 | SMN1; SMN2 (0.54) | — | |
| SCHEMBL3214638 | 0.71 | MAPK1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722746-B2 | Hydroxyphenyl derivatives and biological applications thereof | FAB PHARMA S.A.S. (FR) | 2014-05-13 | — | — | US | disclosed |
| US-20100041658-A1 | Hydroxyphenyl Derivatives and Biological Applications Thereof | FAB PHARMA (FR) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041658-A1 | Hydroxyphenyl Derivatives and Biological Applications Thereof | HPD, HPGDS, EPX | PRSS1 2000/4885TMPRSS15 545/4885AKT1 4283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.