Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 11/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320792 | 0.67 | RAB9A (0.65) | AGTR1RAB9AKDM4EAKR1C3SMN1; SMN2 | |
| SCHEMBL10788888 | 0.65 | KMT2A (0.56) | AGTR1RAB9AKDM4EAKR1C3SMN1; SMN2 | |
| SCHEMBL28095642 | 0.64 | AGTR1 (0.65) | AGTR1RAB9AKDM4EAKR1C3SMN1; SMN2 | |
| SCHEMBL593746 | 0.64 | AKR1C3 (0.73) | AGTR1RAB9AKDM4EAKR1C3SMN1; SMN2 | |
| SCHEMBL6560025 | 0.64 | KMT2A (0.66) | AGTR1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL6899907 | 0.64 | MEN1 (0.65) | AGTR1RAB9AKDM4EAKR1C3SMN1; SMN2 | |
| SCHEMBL18306399 | 0.64 | AKR1C3 (0.83) | AGTR1RAB9AKDM4EAKR1C3SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28169360 | 0.64 | KMT2A (0.54) | AGTR1RAB9AKDM4EAKR1C3SMN1; SMN2 | |
| SCHEMBL19707579 | 0.63 | MRGPRX4 (0.58) | AGTR1RAB9AKDM4EAKR1C3SMN1; SMN2 | |
| SCHEMBL570885 | 0.63 | AGTR1 (0.54) | AGTR1RAB9AKDM4EAKR1C3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010019930-A1 | UREA DERIVATIVES AS INHIBITORS OF MAP KINASES | LOCUS PHARMACEUTICALS, INC. (US) | 2010-02-18 | — | — | WO | disclosed |
| US-20100041642-A1 | UREA INHIBITORS OF MAP KINASES | LOCUS PHARMACEUTICALS, INC. (US) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041642-A1 | UREA INHIBITORS OF MAP KINASES | MAP4K2, MAP3K1, MAP3K20 | AGTR1 2911/4885RAB9A 2804/4885KDM4E 2770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.