Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 2/20 | 0.34 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
| ▸ | NNMT | P40261 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12975517 | 0.85 | RAF1 (0.33) | RAF1PKMYT1SMN1; SMN2PARP1PARP15 | |
| SCHEMBL13316834 | 0.78 | RAF1 (0.38) | RAF1PKMYT1DHODHSMN1; SMN2PARP1 | |
| SCHEMBL13316874 | 0.75 | RAF1 (0.39) | RAF1PKMYT1SMN1; SMN2PARP1PARP15 | |
| SCHEMBL3208908 | 0.74 | RAF1 (0.41) | RAF1PKMYT1SMN1; SMN2PARP1PARP10 | |
| SCHEMBL12971769 | 0.70 | RAF1 (0.31) | RAF1PKMYT1 | |
| SCHEMBL18471225 | 0.69 | SMN1; SMN2 (0.49) | DHODHSMN1; SMN2PARP1PARP10ALDH1A1 | |
| SCHEMBL13316852 | 0.69 | NFKB1 (0.36) | RAF1PKMYT1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13488028 | 0.69 | BRD4 (0.36) | SMN1; SMN2ALDH1A1BRD4 | |
| SCHEMBL1505384 | 0.67 | KDM4E (0.35) | RAF1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1505381 | 0.67 | KDM4E (0.35) | RAF1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100036132-A1 | PROCESS FOR THE PREPARATION OF OPIOD MODULATORS | CAI CHAOZHONG | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036132-A1 | PROCESS FOR THE PREPARATION OF OPIOD MODULATORS | OPRM1, OPRL1, OPRK1 | RAF1 4286/4885PKMYT1 1664/4885DHODH 443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.