Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MDM4 | O15151 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29439334 | 1.00 | CASP3 (0.49) | CASP3KMT2APIN1EPHX2CYP3A4 | |
| SCHEMBL3210403 | 1.00 | CASP3 (0.49) | CASP3KMT2APIN1EPHX2CYP3A4 | |
| SCHEMBL119497 | 0.89 | CASP3 (0.52) | CASP3KMT2APIN1EPHX2CYP3A4 | |
| SCHEMBL1564185 | 0.89 | CASP3 (0.52) | CASP3KMT2APIN1EPHX2CYP3A4 | |
| SCHEMBL6038102 | 0.89 | CASP3 (0.52) | CASP3KMT2APIN1EPHX2CYP3A4 | |
| SCHEMBL118209 | 0.89 | CASP3 (0.52) | CASP3KMT2APIN1EPHX2CYP3A4 | |
| SCHEMBL14019298 | 0.89 | POLB (0.51) | CASP3KMT2APIN1EPHX2CYP3A4 | |
| SCHEMBL1486287 | 0.89 | CASP3 (0.52) | CASP3KMT2APIN1EPHX2CYP3A4 | |
| SCHEMBL1486214 | 0.89 | CASP3 (0.52) | CASP3KMT2APIN1EPHX2CYP3A4 | |
| SCHEMBL30896048 | 0.89 | CASP3 (0.52) | CASP3KMT2APIN1EPHX2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100047841-A1 | SYNTHESIS OF DESACETOXYTUBULYSIN H AND ANALOGS THEREOF | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100047841-A1 | SYNTHESIS OF DESACETOXYTUBULYSIN H AND ANALOGS THEREOF | XDH, XPA, TPX2 | CASP3 690/4885KMT2A 2105/4885PIN1 1641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.