Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | AKR1B10 | O60218 | 5/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA4 | P22748 | 2/20 | 0.53 |
| ▸ | CA6 | P23280 | 2/20 | 0.53 |
| ▸ | CA5A | P35218 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL679321 | 0.89 | MAPT (0.46) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL679884 | 0.89 | MAPT (0.46) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL1565142 | 0.87 | MAPT (0.42) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL5067160 | 0.87 | MAPT (0.42) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL4754676 | 0.85 | LMNA (0.72) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL4761473 | 0.85 | LMNA (0.72) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL1565118 | 0.84 | MAPT (0.40) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL5067125 | 0.84 | MAPT (0.40) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL5019482 | 0.84 | ABCG2 (0.49) | LMNAKMT2AMAPT | |
| SCHEMBL679821 | 0.84 | MAPT (0.40) | LMNAAKR1B10AKR1B1CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048849-A1 | PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP | ROLIC AG (CH) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048849-A1 | PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP | DDC, ALAD, DYNC1LI1 | LMNA 590/4885AKR1B10 1726/4885AKR1B1 2206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.