Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18210849 | 0.90 | PARP10 (0.52) | ALDH1A1TSHRTDP1ESR1CHRM1 | |
| SCHEMBL13498486 | 0.84 | PARP10 (0.50) | TDP1PARP10KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL13498485 | 0.78 | PARP10 (0.55) | ALDH1A1TSHRTDP1PARP10LMNA | |
| SCHEMBL7669589 | 0.77 | LMNA (0.58) | ALDH1A1TSHRTDP1ESR1CHRM1 | |
| SCHEMBL14038141 | 0.76 | CA12 (0.53) | ALDH1A1TSHRTDP1ESR1PARP10 | |
| SCHEMBL8055908 | 0.74 | CA12 (0.58) | ALDH1A1TSHRESR1PARP10LMNA | |
| SCHEMBL6057220 | 0.74 | ALDH1A1 (0.72) | ALDH1A1TSHRTDP1ESR1CHRM1 | |
| SCHEMBL14199955 | 0.74 | LMNA (0.58) | ALDH1A1TSHRTDP1ESR1CHRM1 | |
| SCHEMBL49950 | 0.73 | ALDH1A1 (0.84) | ALDH1A1TSHRTDP1ESR1CHRM1 | |
| SCHEMBL27571108 | 0.73 | LMNA (0.50) | ALDH1A1TSHRTDP1ESR1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100036054-A1 | NOVEL SURFACE ACTIVE POLYMERIC SYSTEMS | UNIVERSITY OF DURHAM (GB) | 2010-02-11 | — | — | US | disclosed |