Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 2/20 | 0.64 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.64 |
| ▸ | GSK3B | P49841 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MGAM | O43451 | 1/20 | 0.56 |
| ▸ | SI | P14410 | 1/20 | 0.56 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.55 |
| ▸ | S100A4 | P26447 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 2/20 | 0.52 |
| ▸ | CASP9 | P55211 | 2/20 | 0.52 |
| ▸ | CASP6 | P55212 | 2/20 | 0.52 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.52 |
| ▸ | TDP2 | O95551 | 1/20 | 0.52 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | IDH1 | O75874 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13499573 | 0.86 | CRHBP (0.68) | CRHBPCRHR2GSK3BGAAMGAM | |
| SCHEMBL13499588 | 0.85 | CRHBP (0.70) | CRHBPCRHR2GSK3BGAAMGAM | |
| SCHEMBL13499587 | 0.84 | CRHBP (0.62) | CRHBPCRHR2GSK3BGAAMGAM | |
| SCHEMBL8310830 | 0.83 | TDP2 (0.75) | CRHBPCRHR2GSK3BCASP7CASP9 | |
| SCHEMBL8310829 | 0.83 | TDP2 (0.75) | CRHBPCRHR2GSK3BCASP7CASP9 | |
| SCHEMBL13499570 | 0.81 | MGAM (0.66) | CRHBPCRHR2GSK3BGAAMGAM | |
| SCHEMBL15091291 | 0.80 | CRHBP (0.71) | CRHBPCRHR2GSK3BIDH1CA2 | |
| SCHEMBL1250835 | 0.80 | CRHBP (0.71) | CRHBPCRHR2GSK3BIDH1CA2 | |
| SCHEMBL1250831 | 0.80 | CRHBP (0.71) | CRHBPCRHR2GSK3BIDH1CA2 | |
| SCHEMBL2065485 | 0.79 | CRHBP (0.72) | CRHBPCRHR2GSK3BGAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0401846-A2 | A direct positive silver halide photographic light-sensitive material and a processing method therefor | KONICA CORPORATION (JP) | 1990-12-12 | — | — | EP | disclosed |