Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1656985 | 0.99 | MEN1 (0.42) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL5271474 | 0.97 | MEN1 (0.41) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL5271477 | 0.97 | MEN1 (0.41) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL3859355 | 0.95 | MEN1 (0.41) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL12267581 | 0.91 | MEN1 (0.43) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL135011 | 0.90 | LMNA (0.41) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL7750107 | 0.87 | MAPT (0.46) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL1714509 | 0.86 | MAPT (0.40) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL559842 | 0.86 | LMNA (0.40) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL137087 | 0.85 | PTPN1 (0.30) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132948-A1 | Cyanine Dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2024-04-25 | — | — | US | disclosed |
| US-11624089-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2023-04-11 | — | — | US | disclosed |
| US-20200232023-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2020-07-23 | — | — | US | disclosed |
| US-10392659-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-20170183501-A1 | Cyanine Dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-06-29 | — | — | US | disclosed |
| US-9441270-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-09-13 | — | — | US | disclosed |
| US-20150072894-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2015-03-12 | — | — | US | disclosed |
| US-8889886-B2 | Cyanine dyes | PACIFIC BIOSCIENCES, INC. (US) | 2014-11-18 | — | — | US | disclosed |
| US-20120052506-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| WO-2012027623-A2 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132948-A1 | Cyanine Dyes | ABCG2, IK, ACR | MEN1 2288/4885LMNA 1823/4885MAPT 2014/4885 |
| US-10392659-B2 | Cyanine dyes | ABCG2, IK, ACR | MEN1 2288/4885LMNA 1823/4885MAPT 2014/4885 |
| US-11624089-B2 | Cyanine dyes | ABCG2, IK, ACR | MEN1 2288/4885LMNA 1823/4885MAPT 2014/4885 |
| US-20120052506-A1 | CYANINE DYES | ABCG2, IK, ACR | MEN1 2288/4885LMNA 1823/4885MAPT 2014/4885 |
| US-20200232023-A1 | CYANINE DYES | ABCG2, IK, ACR | MEN1 2288/4885LMNA 1823/4885MAPT 2014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.