SCHEMBL13502152

SCHEMBL13502152

Cc1cc2c(cc1Oc1ccccc1)-c1cc(Oc3ccccc3)c(C)cc1[Si]2(c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ STK39 Q9UEW8 1/20 0.38
▸ NTRK1 P04629 1/20 0.38
▸ IGF1R P08069 1/20 0.38
▸ FGFR1 P11362 1/20 0.38
▸ NTRK2 Q16620 1/20 0.38
▸ BRD4 O60885 3/20 0.38
▸ FFAR1 O14842 3/20 0.37
▸ FFAR4 Q5NUL3 2/20 0.37
▸ RXRA P19793 1/20 0.35
▸ LTA4H P09960 1/20 0.34
▸ TSHR P16473 1/20 0.34
▸ DHODH Q02127 1/20 0.33
▸ C5AR1 P21730 1/20 0.33
▸ TTR P02766 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13502183 0.94 ALDH1A1 (0.39) STK39NTRK1IGF1RFGFR1NTRK2
SCHEMBL13502220 0.87 NTRK1 (0.38) STK39NTRK1IGF1RFGFR1NTRK2
SCHEMBL13502267 0.82 ALDH1A1 (0.39) STK39NTRK1IGF1RFGFR1NTRK2
SCHEMBL13502161 0.79 FFAR4 (0.49) BRD4FFAR1FFAR4RXRA
SCHEMBL13502164 0.77 HTT (0.43) FFAR4TSHR
SCHEMBL13502191 0.76 ACHE (0.36) —
SCHEMBL12743797 0.74 PTPN11 (0.41) LTA4H
SCHEMBL13502150 0.74 PTPN11 (0.41) LTA4H
SCHEMBL13502190 0.74 ALDH1A1 (0.36) TSHR
SCHEMBL13502188 0.73 LTA4H (0.47) LTA4HTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7662478-B2 Polymer and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-16 — — US disclosed
US-20080103278-A1 NEW POLYMER AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED 2008-05-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080103278-A1 NEW POLYMER AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME CRY1, ARCN1, CORO1A STK39 2743/4885NTRK1 4421/4885IGF1R 665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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