SCHEMBL13502189

SCHEMBL13502189

COc1cc2c(cc1C)[Si](c1ccccc1)(c1ccccc1)c1cc(C)c(N(c3ccccc3)c3ccccc3)cc1-2

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ EGFR P00533 2/20 0.33
▸ CSF1R P07333 2/20 0.33
▸ HTR7 P34969 1/20 0.31
▸ KDM4E B2RXH2 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ ATM Q13315 1/20 0.31
▸ TSHR P16473 1/20 0.30
▸ KDM1A O60341 1/20 0.30
▸ MAOA P21397 1/20 0.30
▸ MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13502264 0.90 EGFR (0.33) EGFRCSF1RHTR7KDM4EMAPT
SCHEMBL13502154 0.89 — —
SCHEMBL13502191 0.79 ACHE (0.36) KDM4EMAPTATM
SCHEMBL13502222 0.78 — —
SCHEMBL13502140 0.77 MAPT (0.33) EGFRCSF1RHTR7KDM4EMAPT
SCHEMBL13502209 0.76 C5 (0.38) —
SCHEMBL13502152 0.72 STK39 (0.38) TSHR
SCHEMBL13502156 0.71 KCNH2 (0.35) —
SCHEMBL13502161 0.71 FFAR4 (0.49) MAPT
SCHEMBL13502160 0.70 CYP2C19 (0.40) KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7662478-B2 Polymer and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-16 — — US disclosed
US-20080103278-A1 NEW POLYMER AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED 2008-05-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080103278-A1 NEW POLYMER AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME CRY1, ARCN1, CORO1A EGFR 4020/4885CSF1R 620/4885HTR7 3533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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