SCHEMBL13502207

SCHEMBL13502207

Cc1cc2c(cc1F)-c1cc(F)c(C)cc1[Si](c1ccccc1)(c1ccccc1)[Si]2(c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GPR3 P46089 1/20 0.42
▸ ACHE P22303 1/20 0.35
▸ MAPT P10636 1/20 0.31
▸ MBNL1 Q9NR56 1/20 0.30
▸ HTR7 P34969 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13502147 0.85 GPR3 (0.42) GPR3ACHEMAPTMBNL1
SCHEMBL13502219 0.78 ESR2 (0.43) MAPTHTR7
SCHEMBL14188271 0.75 — —
SCHEMBL13502223 0.74 LDHA (0.40) HTR7
SCHEMBL13502221 0.73 RXRA (0.34) MAPT
SCHEMBL13502222 0.73 — —
SCHEMBL13502243 0.71 APP (0.38) MAPT
SCHEMBL13502245 0.71 PDE3B (0.42) MAPT
SCHEMBL13502244 0.71 TTR (0.41) MAPT
SCHEMBL13502203 0.71 ELANE (0.41) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7662478-B2 Polymer and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-16 — — US disclosed
US-20080103278-A1 NEW POLYMER AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED 2008-05-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080103278-A1 NEW POLYMER AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME CRY1, ARCN1, CORO1A GPR3 1797/4885ACHE 4589/4885MAPT 2640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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