Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10030197 | 0.87 | ALDH1A1 (0.52) | MTNR1AMTNR1BLMNAHSD17B10MAPT | |
| SCHEMBL8668866 | 0.86 | MAPT (0.54) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL16657521 | 0.83 | MAPT (0.47) | BACE1MTNR1AMTNR1BESR2NPC1 | |
| SCHEMBL13503150 | 0.81 | CA1 (0.53) | ESR2NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL12434531 | 0.80 | THRB (0.46) | ESR2NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL14242751 | 0.79 | LMNA (0.55) | NPC1LMNAMAPTALDH1A1KMT2A | |
| SCHEMBL19721780 | 0.79 | ALDH1A1 (0.56) | BACE1ESR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9658508 | 0.78 | MTNR1A (0.59) | MTNR1AMTNR1BSMN1; SMN2LMNAMAPT | |
| SCHEMBL12818123 | 0.78 | MAOB (0.51) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL28821681 | 0.78 | TDP1 (0.50) | NPC1RAB9ASMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7659353-B2 | Hyperbranched polymers | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2010-02-09 | — | — | US | disclosed |
| US-7659353-B2 | Hyperbranched polymers | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2010-02-09 | — | — | US | disclosed |