Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CD38 | P28907 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 3/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5372889 | 0.92 | KDM4E (0.39) | KDM4ESMN1; SMN2CD38NNMTMAPK8 | |
| SCHEMBL1003868 | 0.86 | KDM4E (0.44) | KDM4ESMN1; SMN2CD38NNMTMAPK8 | |
| SCHEMBL4951717 | 0.82 | SMN1; SMN2 (0.39) | KDM4ESMN1; SMN2NNMTL3MBTL1POLB | |
| SCHEMBL14604836 | 0.82 | KDM4E (0.44) | KDM4ENNMTMAPK8L3MBTL1POLB | |
| SCHEMBL6186161 | 0.78 | PARP1 (0.41) | KDM4ESMN1; SMN2MAPK8PARP1 | |
| SCHEMBL3828018 | 0.78 | SMN1; SMN2 (0.39) | KDM4ESMN1; SMN2NNMTL3MBTL1POLB | |
| SCHEMBL3025730 | 0.78 | DHFR (0.36) | KDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL24937343 | 0.77 | TSHR (0.50) | KDM4EL3MBTL1POLB | |
| SCHEMBL28053273 | 0.77 | KDM4E (0.36) | KDM4ESMN1; SMN2PARP1CDC7 | |
| SCHEMBL580070 | 0.77 | POLB (0.39) | KDM4ESMN1; SMN2L3MBTL1POLBPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2439188-B1 | p-Menthane-3,8-diol derivatives and insect repellents comprising them | SELKIS SAS (FR) | 2012-10-31 | — | — | EP | claimed |