Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | APP | P05067 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | SNCA | P37840 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13508379 | 0.90 | MLNR (0.46) | ALDH1A1APPMAPTSNCAKMT2A | |
| SCHEMBL13811038 | 0.85 | MAPT (0.40) | ALDH1A1APPMAPTSNCAKMT2A | |
| SCHEMBL13508401 | 0.80 | CYP19A1 (0.55) | ALDH1A1APPMAPTSNCAKMT2A | |
| SCHEMBL14570730 | 0.77 | CYP19A1 (0.52) | ALDH1A1APPMAPTSNCAKMT2A | |
| SCHEMBL13508381 | 0.74 | HTR6 (0.46) | ALDH1A1APPMAPTSNCAKMT2A | |
| SCHEMBL13508434 | 0.72 | CYP19A1 (0.44) | ALDH1A1MAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL13508457 | 0.72 | CYP19A1 (0.39) | ALDH1A1APPMAPTSNCAKMT2A | |
| SCHEMBL13508455 | 0.72 | MIF (0.54) | ALDH1A1APPMAPTSNCAKMT2A | |
| SCHEMBL13508410 | 0.72 | MAOB (0.48) | ALDH1A1APPMAPTSNCAKMT2A | |
| SCHEMBL15468989 | 0.72 | MAPT (0.43) | ALDH1A1APPMAPTSNCAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761962-B1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2010-02-03 | — | — | EP | disclosed |
| US-20090159874-A1 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
| US-20090159874-A1 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090159874-A1 | Organic electroluminescent devices | LEF1, NCS1, CRY1 | ALDH1A1 18/4885APP 1847/4885MAPT 572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.