Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 16/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 15/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13507665 | 0.88 | CYP11B2 (0.51) | CYP11B2CYP11B1CYP1A2CYP17A1CYP19A1 | |
| SCHEMBL13511364 | 0.86 | MAOA (0.41) | CYP11B2CYP11B1FGFR1TDP2CHEK1 | |
| SCHEMBL13511537 | 0.82 | PGR (0.34) | CYP11B2CYP11B1CHEK1MAP4K4FYN | |
| SCHEMBL13511781 | 0.72 | AKT1 (0.34) | CYP11B2CYP11B1CHEK1METPIM1 | |
| SCHEMBL13507589 | 0.71 | MEN1 (0.38) | FGFR1TDP2CDK9CHEK1AURKA | |
| SCHEMBL13511777 | 0.70 | KMT2A (0.33) | CHEK1 | |
| SCHEMBL13508064 | 0.68 | PGR (0.39) | FGFR1CDK9CHEK1MAP4K4ABL1 | |
| SCHEMBL1762438 | 0.68 | CYP11B1 (1.00) | CYP11B2CYP11B1CYP1A2CYP17A1CYP19A1 | |
| SCHEMBL25026632 | 0.67 | CYP11B2 (0.57) | CYP11B2CYP11B1CYP1A2CYP17A1CYP19A1 | |
| SCHEMBL27856084 | 0.66 | CYP11B2 (0.52) | CYP11B2CYP11B1CYP1A2CYP17A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2145936-A2 | Fluorene and pyrene derivatives and organic electroluminescent device using the same | Gracel Display Inc. (KR) | 2010-01-20 | — | — | EP | disclosed |