Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.43 |
| ▸ | CNR2 | P34972 | 4/20 | 0.43 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | STAT6 | P42226 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14065381 | 0.83 | CNR1 (0.44) | CNR1CNR2CXCR5KDM2BHPGDS | |
| SCHEMBL4116945 | 0.81 | HPGDS (0.58) | CNR1CNR2CXCR5KDM2BHPGDS | |
| SCHEMBL4114890 | 0.81 | CNR1 (0.50) | CNR1CNR2CXCR5KDM2BHPGDS | |
| SCHEMBL4115161 | 0.77 | GRM2 (0.46) | CNR1CNR2CXCR5KDM2BHPGDS | |
| SCHEMBL249578 | 0.76 | NR4A1 (0.52) | CNR1CNR2CXCR5SCN9AALDH1A1 | |
| SCHEMBL14065383 | 0.75 | LMNA (0.55) | CNR1CNR2CXCR5HPGDSALDH1A1 | |
| SCHEMBL401068 | 0.75 | CNR1 (0.47) | CNR1CNR2CXCR5KDM2BCES2 | |
| SCHEMBL4031210 | 0.75 | ALDH1A1 (0.57) | CNR1CNR2CXCR5KDM2BSCN9A | |
| SCHEMBL2174146 | 0.75 | ATM (0.60) | CNR1CNR2CXCR5KDM2BSCN9A | |
| SCHEMBL29392762 | 0.75 | CNR1 (0.47) | CNR1CNR2CXCR5KDM2BCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575502-B1 | COMPOSITIONS AND METHODS INVOLVING NUCLEAR HORMONE RECEPTOR SITE II | BRISTOL MYERS SQUIBB CO (US) | 2010-01-20 | — | — | EP | disclosed |