Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17992901 | 0.83 | ALDH1A1 (0.34) | ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL20290380 | 0.76 | ALDH1A1 (0.36) | ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL15685043 | 0.76 | — | — | |
| SCHEMBL12489659 | 0.75 | ALDH1A1 (0.33) | ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL30534356 | 0.75 | ALDH1A1 (0.41) | ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL16359824 | 0.74 | ALDH1A1 (0.33) | ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL14546925 | 0.74 | MMP9 (0.37) | ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL23056649 | 0.72 | ALDH1A1 (0.33) | ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL18123722 | 0.72 | MMP9 (0.38) | ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL14518636 | 0.72 | LAP3 (0.36) | ALDH1A1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376524-B1 | DERIVATIVES OF CYCLOSPORIN A | CYPRALIS LTD (GB) | 2017-03-15 | — | — | EP | disclosed |
| WO-2010002428-A2 | NOVEL MACROCYCLIC PEPTIDES | SCYNEXIS, INC. (US) | 2010-01-07 | — | — | WO | disclosed |
| WO-2007041632-A2 | METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF HEPATITIS C INFECTION | SCYNEXIS, INC. (US) | 2007-04-12 | — | — | WO | disclosed |