Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.62 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086491 | 1.00 | AGTR1 (0.62) | AGTR1HKDC1LMNAMEN1KMT2A | |
| SCHEMBL7086789 | 1.00 | AGTR1 (0.62) | AGTR1HKDC1LMNAMEN1KMT2A | |
| SCHEMBL8738064 | 0.91 | CTH (0.55) | AGTR1HKDC1LMNAMEN1KMT2A | |
| SCHEMBL29852200 | 0.91 | CTH (0.55) | AGTR1HKDC1LMNAMEN1KMT2A | |
| SCHEMBL31690656 | 0.84 | AGTR1 (0.70) | AGTR1HKDC1LMNAMEN1KMT2A | |
| SCHEMBL13522803 | 0.82 | TOP2A (0.68) | AGTR1HKDC1LMNAMEN1KMT2A | |
| SCHEMBL29896251 | 0.82 | TOP2A (0.68) | AGTR1HKDC1LMNAMEN1KMT2A | |
| SCHEMBL29896301 | 0.82 | TOP2A (0.68) | AGTR1HKDC1LMNAMEN1KMT2A | |
| SCHEMBL5522740 | 0.81 | HKDC1 (0.67) | AGTR1HKDC1LMNAMEN1KMT2A | |
| SCHEMBL13522802 | 0.81 | AGTR1 (0.67) | AGTR1HKDC1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030166692-A1 | Composition useful as anticancer drug and radiosensitizer | PHARMGENIA CO., LTD. OF DEVELOPMENTAL GENETICS LABORATORY, | 2003-09-04 | — | — | US | disclosed |
| US-20030166692-A1 | Composition useful as anticancer drug and radiosensitizer | PHARMGENIA CO., LTD. OF DEVELOPMENTAL GENETICS LABORATORY, | 2003-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166692-A1 | Composition useful as anticancer drug and radiosensitizer | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HDAC5, HCCS | AGTR1 4549/4885HKDC1 94/4885LMNA 4062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.