Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2926366 | 0.86 | SMN1; SMN2 (0.34) | SMN1; SMN2CNR1CNR2ALDH1A1LMNA | |
| SCHEMBL2930475 | 0.85 | SMN1; SMN2 (0.39) | SMN1; SMN2CNR1CNR2ALDH1A1NPC1 | |
| SCHEMBL27603443 | 0.82 | SMN1; SMN2 (0.40) | SMN1; SMN2CNR1CNR2MAPT | |
| SCHEMBL5409719 | 0.81 | SMN1; SMN2 (0.41) | SMN1; SMN2CNR1CNR2ALDH1A1HTT | |
| SCHEMBL2923471 | 0.80 | SMN1; SMN2 (0.35) | SMN1; SMN2CNR1CNR2ALDH1A1NPC1 | |
| SCHEMBL5423046 | 0.79 | ALDH1A1 (0.37) | CNR1CNR2ALDH1A1NPC1RAB9A | |
| SCHEMBL4180955 | 0.76 | KDM4E (0.31) | ALDH1A1LMNA | |
| SCHEMBL5416063 | 0.76 | KDM4E (0.43) | SMN1; SMN2ALDH1A1HTTLMNAMAPT | |
| SCHEMBL8920720 | 0.75 | MAPT (0.41) | SMN1; SMN2ALDH1A1HTTLMNAMAPT | |
| SCHEMBL4193744 | 0.73 | ALDH1A1 (0.37) | SMN1; SMN2CNR1CNR2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642360-B2 | Composition for dyeing keratinous fibers comprising at least one diamino-N,N-dihydropyrazolone derivative | L'OREAL S.A. (FR) | 2010-01-05 | — | — | US | disclosed |
| US-7642360-B2 | Composition for dyeing keratinous fibers comprising at least one diamino-N,N-dihydropyrazolone derivative | L'OREAL S.A. (FR) | 2010-01-05 | — | — | US | disclosed |
| US-20080071092-A1 | Composition for dyeing keratinous fibers comprising at least one diamino-N,N-dihydropyrazolone derivative | L'OREAL S.A. | 2008-03-20 | — | — | US | disclosed |
| US-20080071092-A1 | Composition for dyeing keratinous fibers comprising at least one diamino-N,N-dihydropyrazolone derivative | L'OREAL S.A. | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080071092-A1 | Composition for dyeing keratinous fibers comprising at least one diamino-N,N-dihydropyrazolone derivative | KRT18, DAO, AOC1 | SMN1; SMN2 4116/4885CNR1 4800/4885CNR2 4676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.