SCHEMBL1352811

SCHEMBL1352811

[c]1ccccc1C12CC3CC(C1)CC(c1[c]cccc1)(C3)C2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.42
GRIN3B O60391 1/20 0.42
GRIN1 Q05586 1/20 0.42
GRIN2A Q12879 1/20 0.42
GRIN2B Q13224 1/20 0.42
GRIN2C Q14957 1/20 0.42
GRIN3A Q8TCU5 1/20 0.42
PGR P06401 4/20 0.34
ALDH1A1 P00352 5/20 0.33
HSD11B1 P28845 2/20 0.33
LMNA P02545 3/20 0.32
MEN1 O00255 4/20 0.31
KMT2A Q03164 4/20 0.31
HTT P42858 2/20 0.31
KDM4E B2RXH2 1/20 0.31
RAD52 P43351 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30
GFER P55789 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL182120 0.89 ALDH1A1 (0.38) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL11331059 0.79
SCHEMBL8098105 0.75
SCHEMBL1352810 0.74 PGR (0.34) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1353428 0.72 HSD11B1 (0.34) HSD11B1
SCHEMBL1352813 0.70 GRIN2D (0.75) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL18317420 0.66 LMNA (0.47) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL17965922 0.66 ALDH1A1 (0.42) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1264419 0.66 ALDH1A1 (0.38) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL10904397 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8372942-B2 Polycarbonate resin, coating liquid containing same, and electrophotographic photosensitive body IDEMITSU KOSAN CO., LTD. (JP) 2013-02-12 US claimed
US-20110287354-A1 POLYCARBONATE RESIN, COATING LIQUID CONTAINING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY IDEMITSU KOSAN CO., LTD. (JP) 2011-11-24 US claimed
EP-2378363-A1 POLYCARBONATE RESIN, COATING LIQUID CONTAINING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY Idemitsu Kosan Co., Ltd. (JP) 2011-10-19 EP claimed
US-8372942-B2 Polycarbonate resin, coating liquid containing same, and electrophotographic photosensitive body IDEMITSU KOSAN CO., LTD. (JP) 2013-02-12 US disclosed
US-20110287354-A1 POLYCARBONATE RESIN, COATING LIQUID CONTAINING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY IDEMITSU KOSAN CO., LTD. (JP) 2011-11-24 US disclosed
EP-2378363-A1 POLYCARBONATE RESIN, COATING LIQUID CONTAINING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY Idemitsu Kosan Co., Ltd. (JP) 2011-10-19 EP disclosed