Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.62 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1350186 | 0.96 | MEN1 (0.73) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1350184 | 0.96 | MEN1 (0.73) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1350109 | 0.96 | ADRB1 (0.67) | MEN1KMT2AALDH1A1SMN1; SMN2ADRB1 | |
| SCHEMBL1350111 | 0.96 | ADRB1 (0.67) | MEN1KMT2AALDH1A1SMN1; SMN2ADRB1 | |
| SCHEMBL1351181 | 0.91 | ATM (0.66) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1351183 | 0.91 | ATM (0.66) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1351928 | 0.84 | NPC1 (0.63) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1351929 | 0.84 | NPC1 (0.63) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3936533 | 0.82 | LMNA (0.61) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1350520 | 0.82 | LMNA (0.61) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110288104-A1 | Beta-3 receptor ligands and their use in therapy | UNIVERSITA' DEGLI STUDI DI BARI (IT) | 2011-11-24 | — | — | US | disclosed |
| US-8017613-B2 | Beta-3 receptor ligands and their use in therapy | UNIVERSITA' DEGLI STUDI DI BARI (IT) | 2011-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288104-A1 | Beta-3 receptor ligands and their use in therapy | ADRB3, ADRB2, ADRB1 | MEN1 3963/4885KMT2A 4336/4885ALDH1A1 1882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.