Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 13/20 | 0.65 |
| ▸ | HTR7 | P34969 | 1/20 | 0.65 |
| ▸ | HTR2A | P28223 | 12/20 | 0.63 |
| ▸ | DRD2 | P14416 | 10/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13533153 | 0.92 | HTR1A (0.65) | HTR1AHTR7HTR2ADRD2KCNH2 | |
| SCHEMBL6105283 | 0.82 | HTR1A (0.70) | HTR1AHTR7HTR2ADRD2KCNH2 | |
| SCHEMBL13533148 | 0.82 | HTR1A (0.67) | HTR1AHTR7HTR2ADRD2KCNH2 | |
| SCHEMBL6104289 | 0.81 | HTR1A (0.69) | HTR1AHTR7HTR2ADRD2KCNH2 | |
| SCHEMBL6105750 | 0.81 | HTR1A (0.69) | HTR1AHTR7HTR2ADRD2KCNH2 | |
| SCHEMBL6104594 | 0.81 | HTR1A (0.69) | HTR1AHTR7HTR2ADRD2KCNH2 | |
| SCHEMBL9520828 | 0.80 | HTR1A (0.59) | HTR1AHTR7HTR2ADRD2KCNH2 | |
| Hydrochloric Acid SCHEMBL6104630 | 0.80 | HTR1A (0.67) | HTR1AHTR7HTR2ADRD2KCNH2 | |
| SCHEMBL10845693 | 0.79 | HTR1A (0.72) | HTR1AHTR7HTR2ADRD2KCNH2 | |
| SCHEMBL8812763 | 0.78 | HTR1A (0.56) | HTR1AHTR7HTR2ADRD2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009983-A1 | 5 HT RECEPTOR MEDIATED NEUROGENESIS | BRAINCELLS, INC. (US) | 2010-01-14 | — | — | US | disclosed |
| US-20100009983-A1 | 5 HT RECEPTOR MEDIATED NEUROGENESIS | BRAINCELLS, INC. (US) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009983-A1 | 5 HT RECEPTOR MEDIATED NEUROGENESIS | HTR6, GAP43, HTR5A | HTR1A 7/4885HTR7 11/4885HTR2A 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.