Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | PPIA | P62937 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13533397 | 0.93 | MCHR1 (0.45) | SLC6A4HTR1AMTNR1AMCHR1SLC6A2 | |
| SCHEMBL13533385 | 0.84 | PARP1 (0.41) | SLC6A4HTR1AMTNR1ASLC6A2HRH1 | |
| SCHEMBL13534211 | 0.84 | SLC6A4 (0.45) | SLC6A4HTR1AMTNR1AMCHR1SLC6A2 | |
| SCHEMBL13533375 | 0.82 | MTNR1A (0.60) | SLC6A4HTR1AMTNR1AMCHR1NFKB1 | |
| SCHEMBL31561756 | 0.79 | SLC6A4 (0.43) | SLC6A4HTR1AMTNR1ASLC6A2HRH1 | |
| SCHEMBL7827780 | 0.79 | SLC6A4 (0.43) | SLC6A4HTR1AMTNR1ASLC6A2HRH1 | |
| SCHEMBL4191964 | 0.79 | KDM4E (0.47) | SLC6A4HTR1AMTNR1ASLC6A2HRH1 | |
| SCHEMBL13533370 | 0.79 | MTNR1A (0.56) | SLC6A4HTR1AMTNR1AMCHR1 | |
| SCHEMBL13533373 | 0.75 | MTNR1A (0.49) | SLC6A4HTR1AMTNR1AMCHR1HTT | |
| SCHEMBL13197080 | 0.75 | MTNR1A (0.59) | SLC6A4HTR1AMTNR1AMCHR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009983-A1 | 5 HT RECEPTOR MEDIATED NEUROGENESIS | BRAINCELLS, INC. (US) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009983-A1 | 5 HT RECEPTOR MEDIATED NEUROGENESIS | HTR6, GAP43, HTR5A | SLC6A4 60/4885HTR1A 7/4885MTNR1A 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.