Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 4/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4403130 | 0.79 | GABRA5 (0.48) | GABRA5CSNK2A2CSNK2A1KCNH2HPGDS | |
| SCHEMBL2397226 | 0.78 | GABRA5 (0.44) | GABRA5DRD3DRD2GPR119KCNH2 | |
| SCHEMBL2393680 | 0.78 | GABRA5 (0.44) | GABRA5DRD3DRD2GPR119KCNH2 | |
| SCHEMBL2391515 | 0.77 | GABRA5 (0.45) | GABRA5DRD3DRD2GPR119CSNK2A2 | |
| SCHEMBL13534689 | 0.72 | GPR119 (0.49) | GPR119KCNH2 | |
| SCHEMBL12106761 | 0.67 | GUCY1B2 (0.38) | GABRA5DRD3DRD2GPR119 | |
| SCHEMBL2392621 | 0.66 | GPR119 (0.47) | GPR119KCNH2HPGDS | |
| SCHEMBL2392624 | 0.66 | GPR119 (0.47) | GPR119KCNH2HPGDS | |
| SCHEMBL12106773 | 0.65 | JAK2 (0.35) | GABRA5DRD3DRD2GPR119 | |
| SCHEMBL2398405 | 0.65 | GPR119 (0.42) | GABRA5GPR119HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010004344-A1 | PIPERIDINE GPCR AGONISTS | PROSIDION LIMITED (GB) | 2010-01-14 | — | — | WO | disclosed |