Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 2/20 | 0.48 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4403111 | 0.82 | ITGB3 (0.42) | PLATHPGDSRAB9AEGLN1ITGB3 | |
| SCHEMBL2391515 | 0.80 | GABRA5 (0.45) | GABRA5HPGDSCSNK2A2CSNK2A1RAB9A | |
| SCHEMBL2393680 | 0.80 | GABRA5 (0.44) | GABRA5RAB9AGABRA1KCNH2 | |
| SCHEMBL2397226 | 0.80 | GABRA5 (0.44) | GABRA5RAB9AGABRA1KCNH2 | |
| SCHEMBL4400842 | 0.79 | NNMT (0.49) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL1295961 | 0.79 | DHODH (0.44) | ITGB3ITGA2B | |
| SCHEMBL13534650 | 0.79 | GABRA5 (0.40) | GABRA5HPGDSBTKCSNK2A2CSNK2A1 | |
| SCHEMBL11918183 | 0.79 | GPR119 (0.49) | PLATHPGDSRAB9ASCN9AKCNH2 | |
| Hydrochloric Acid SCHEMBL1296024 | 0.78 | ITGB3 (0.41) | ITGB3ITGA2B | |
| SCHEMBL1295825 | 0.77 | GABRA5 (0.43) | GABRA5PLATRAB9AITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321308-B9 | PIPERIDINE GPCR AGONISTS | PROSIDION LTD (GB) | 2012-08-08 | — | — | EP | disclosed |
| EP-2321308-B1 | PIPERIDINE GPCR AGONISTS | PROSIDION LTD (GB) | 2012-05-09 | — | — | EP | disclosed |