Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4397843 | 0.78 | GPR119 (0.42) | GPR119 | |
| SCHEMBL11918183 | 0.77 | GPR119 (0.49) | GPR119CRBNHRH3KCNH2RAB9A | |
| SCHEMBL2397230 | 0.76 | GPR119 (0.51) | GPR119CRBNHRH3KCNH2DHODH | |
| SCHEMBL2397233 | 0.76 | GPR119 (0.51) | GPR119CRBNHRH3KCNH2DHODH | |
| SCHEMBL4400648 | 0.72 | GPR119 (0.43) | GPR119HRH3 | |
| SCHEMBL13534650 | 0.72 | GABRA5 (0.40) | GPR119KCNH2 | |
| SCHEMBL2398388 | 0.72 | GPR119 (0.54) | GPR119CRBNHRH3KCNH2RAB9A | |
| SCHEMBL1922857 | 0.71 | GPR119 (0.68) | GPR119 | |
| SCHEMBL14621454 | 0.70 | GPR119 (0.49) | GPR119CRBNKCNH2 | |
| SCHEMBL3614267 | 0.70 | GPR119 (0.51) | GPR119CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010004344-A1 | PIPERIDINE GPCR AGONISTS | PROSIDION LIMITED (GB) | 2010-01-14 | — | — | WO | disclosed |