Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.62 |
| ▸ | CTSL | P07711 | 3/20 | 0.62 |
| ▸ | CTSS | P25774 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.58 |
| ▸ | ITGAV | P06756 | 1/20 | 0.58 |
| ▸ | CTSB | P07858 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.55 |
| ▸ | TACR1 | P25103 | 3/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829026 | 0.92 | POLB (0.56) | CTSKCTSLCTSSPOLBITGB3 | |
| SCHEMBL13536740 | 0.91 | POLB (0.63) | CTSKCTSLCTSSPOLBCTSB | |
| SCHEMBL30427977 | 0.87 | ITGB3 (0.63) | CTSKCTSLCTSSITGB3ITGAV | |
| SCHEMBL13536734 | 0.87 | ITGB3 (0.63) | CTSKCTSLCTSSITGB3ITGAV | |
| SCHEMBL9825830 | 0.87 | TYR (0.58) | CTSKCTSLCTSSITGB3ITGAV | |
| SCHEMBL5288135 | 0.87 | TYR (0.58) | CTSKCTSLCTSSITGB3ITGAV | |
| SCHEMBL479010 | 0.86 | TACR1 (0.68) | CTSKCTSLCTSSITGB3CTSB | |
| SCHEMBL26661077 | 0.86 | TACR1 (0.68) | CTSKCTSLCTSSITGB3CTSB | |
| SCHEMBL7372270 | 0.86 | TACR1 (0.68) | CTSKCTSLCTSSITGB3CTSB | |
| SCHEMBL220648 | 0.86 | TACR1 (0.68) | CTSKCTSLCTSSITGB3CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7649015-B2 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | GILEAD SCIENCES, INC. | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | PPA1, PNP, PPME1 | CTSK 298/4885CTSL 179/4885CTSS 277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.