Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CTSL | P07711 | 3/20 | 0.55 |
| ▸ | CTSS | P25774 | 3/20 | 0.55 |
| ▸ | CTSK | P43235 | 3/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.53 |
| ▸ | ITGAV | P06756 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | PLAT | P00750 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13536744 | 0.92 | CTSK (0.62) | POLBCTSLCTSSCTSKITGB3 | |
| SCHEMBL7084689 | 0.87 | ITGB3 (0.66) | CTSLCTSSCTSKITGB3ITGA2B | |
| SCHEMBL8717685 | 0.87 | ITGB3 (0.66) | CTSLCTSSCTSKITGB3ITGA2B | |
| SCHEMBL13536740 | 0.83 | POLB (0.63) | POLBCTSLCTSSCTSKCTSB | |
| SCHEMBL30427977 | 0.82 | ITGB3 (0.63) | CTSLCTSSCTSKITGB3ITGAV | |
| SCHEMBL13536734 | 0.82 | ITGB3 (0.63) | CTSLCTSSCTSKITGB3ITGAV | |
| SCHEMBL9829121 | 0.81 | CTSB (0.60) | CTSLCTSSCTSKCTSB | |
| Aniline SCHEMBL8510048 | 0.80 | ALDH1A1 (0.59) | CTSLCTSSCTSKITGB3ITGA2B | |
| SCHEMBL15630497 | 0.80 | ALDH1A1 (0.65) | CTSLCTSSCTSKITGB3ITGA2B | |
| SCHEMBL17007549 | 0.80 | ALDH1A1 (0.65) | CTSLCTSSCTSKITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |