Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | CACNB4 | O00305 | 5/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 5/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 5/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 5/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 5/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 5/20 | 0.39 |
| ▸ | CACNB3 | P54284 | 5/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 5/20 | 0.39 |
| ▸ | CACNG7 | P62955 | 5/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13537213 | 0.92 | BCL6 (0.44) | BCL6ICMTHRH2 | |
| SCHEMBL13537232 | 0.84 | BCL6 (0.43) | HDAC3HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL3351825 | 0.82 | ACHE (0.44) | HDAC3HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL3352252 | 0.81 | CACNB4 (0.43) | HDAC3HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL13537417 | 0.79 | CACNB4 (0.41) | HDAC3HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL3356042 | 0.78 | CACNB4 (0.52) | MTNR1AMTNR1BCACNB4CACNA1ACACNA1G | |
| SCHEMBL3354509 | 0.77 | CACNB4 (0.54) | MTNR1AMTNR1BCACNB4CACNA1ACACNA1G | |
| SCHEMBL13537209 | 0.77 | CNR2 (0.41) | NPSR1CNR2 | |
| SCHEMBL3354038 | 0.74 | NR1H2 (0.46) | BCL6ICMTLMNA | |
| SCHEMBL13537299 | 0.74 | CNR2 (0.52) | NPSR1HRH2CNR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |