Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 3/20 | 0.43 |
| ▸ | HTR6 | P50406 | 5/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | CACNB4 | O00305 | 3/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 3/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 3/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.39 |
| ▸ | CACNB3 | P54284 | 3/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.39 |
| ▸ | CACNG7 | P62955 | 3/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13537213 | 0.85 | BCL6 (0.44) | BCL6HTR6ICMT | |
| SCHEMBL13537295 | 0.84 | HDAC3 (0.42) | BCL6HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL3357970 | 0.82 | NR1H2 (0.47) | HTR6CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL13537296 | 0.78 | PDE4A (0.37) | HTR6HDAC1 | |
| SCHEMBL3352715 | 0.78 | HTR7 (0.59) | HTR6CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL13537255 | 0.76 | LMNA (0.46) | HTR6HDAC8HDAC6ICMTALDH1A1 | |
| SCHEMBL13537231 | 0.75 | CNR2 (0.42) | HTR6HDAC1ALDH1A1POLB | |
| SCHEMBL13537352 | 0.73 | CACNB4 (0.46) | HDAC8HDAC6CACNB4CACNA1ACACNA1G | |
| SCHEMBL13537279 | 0.69 | HTR6 (0.58) | HTR6HTR7 | |
| SCHEMBL3354038 | 0.68 | NR1H2 (0.46) | BCL6HTR6ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |