Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 6/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13537320 | 0.75 | ALOX5 (0.42) | ALDH1A1SMN1; SMN2MEN1RAB9AKMT2A | |
| SCHEMBL13537323 | 0.74 | ALOX5 (0.42) | ALDH1A1SMN1; SMN2MEN1RAB9AKMT2A | |
| SCHEMBL13537346 | 0.74 | KMT2A (0.44) | ALDH1A1RAB9AKMT2ANPC1NR4A2 | |
| SCHEMBL13537324 | 0.72 | ALOX5 (0.46) | ALDH1A1SMN1; SMN2MEN1RAB9AKMT2A | |
| SCHEMBL13537598 | 0.69 | NQO2 (0.44) | MEN1RAB9AKMT2AHTR2AHTR1D | |
| SCHEMBL13896419 | 0.66 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2MEN1RAB9AKMT2A | |
| SCHEMBL7497813 | 0.65 | NR4A2 (0.43) | ALDH1A1SMN1; SMN2MEN1RAB9AKMT2A | |
| SCHEMBL599384 | 0.65 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MEN1RAB9AKMT2A | |
| SCHEMBL23940250 | 0.64 | BRD4 (0.71) | ALDH1A1SMN1; SMN2KMT2ANR4A2BRD4 | |
| SCHEMBL4421193 | 0.63 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |