Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13537320 | 0.89 | ALOX5 (0.42) | ALOX5ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL13537323 | 0.88 | ALOX5 (0.42) | ALOX5ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL13537346 | 0.88 | KMT2A (0.44) | ALOX5ALDH1A1GAAKMT2ANPC1 | |
| SCHEMBL1558335 | 0.81 | ALDH1A1 (0.60) | ALOX5ALDH1A1MAPTGAALMNA | |
| SCHEMBL3358890 | 0.80 | POLB (0.52) | ALOX5ALDH1A1MAPTGAALMNA | |
| SCHEMBL13537325 | 0.72 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL13114473 | 0.71 | KDM4E (0.59) | ALDH1A1MAPTGAALMNAMEN1 | |
| SCHEMBL1559389 | 0.70 | KMT2A (0.65) | ALOX5ALDH1A1MAPTGAALMNA | |
| SCHEMBL3358211 | 0.68 | MAPT (0.47) | ALOX5ALDH1A1MAPTGAALMNA | |
| SCHEMBL23940225 | 0.68 | HDAC6 (0.56) | ALDH1A1MAPTLMNAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |